Joshaghani Mahmood, Soleimani Mohammad, Foroutan Alireza, Yaseri Mehdi
Eye Research Center, Rassoul Akram Hospital, Tehran, Iran.
Eye Research Center, Farabi Eye Hospital, Tehran, Iran.
Middle East Afr J Ophthalmol. 2015 Oct-Dec;22(4):495-501. doi: 10.4103/0974-9233.164610.
To evaluate the long-term visual outcomes and complications of the piggyback intraocular lens (IOL) implantation compared to aphakia for infantile cataract.
In a comparative study from 1998 to 2007, piggyback IOL implantation (piggyback IOL group) was performed for 14 infants (23 eyes) with infantile cataract and 20 infants (32 eyes) who were aphakic (aphakia group) after infantile cataract surgery. Data were collected on logMAR visual acuity, and postoperative complications over a mean follow-up time of 6.2 ± 1.7 years and 5.8 ± 1.7 years.
The mean age at surgery was 7.5 ± 0.6 months and 6.0 ± 3.3 months for the piggyback and the aphakic group respectively (P > 0.05). At the last follow-up visit, visual acuity was 0.85 ± 0.73 (median = 0.70, interquartile range = 0.3-1.32) in the piggyback IOL group and 0.89 ± 0.56 (median = 0.86, interquartile range = 0.50-1.24) in the aphakic group (P > 0.05). There was a positive relationship between age and visual outcomes in the aphakic group (r = 0.4, P = 0.04) but not in the piggyback IOL group (P = 0.48). There was no significant difference between the mean myopic shift in the piggyback IOL group (-5.28 ± 1.06 D) and the aphakic group (-5.10 ± 1.02 D) (P > 0.05). The incidence of reoperation due to complications in piggyback IOL group was higher than aphakic group (%48 vs. %16, respectively, P ≤ 0.01). However, in patients older than 6 months, this risk was not significantly different compared to the aphakic group.
Although piggyback IOL implantation for infantile cataract is optically acceptable as a treatment option, there is no significant difference in visual outcomes compared to aphakia. The incidence in reoperation due to complications in patients aged 6 months or younger is higher than those treated with aphakia.
评估与无晶状体眼相比,二期人工晶状体(IOL)植入治疗婴幼儿白内障的长期视觉效果及并发症。
在一项1998年至2007年的对照研究中,对14例(23只眼)患有婴幼儿白内障的婴儿行二期IOL植入术(二期IOL组),以及对20例(32只眼)婴幼儿白内障手术后形成无晶状体眼的婴儿(无晶状体眼组)进行研究。收集了对数最小分辨角视力(logMAR)及术后并发症的数据,平均随访时间分别为6.2±1.7年和5.8±1.7年。
二期IOL组和无晶状体眼组手术时的平均年龄分别为7.5±0.6个月和6.0±3.3个月(P>0.05)。在最后一次随访时,二期IOL组的视力为0.85±0.73(中位数=0.70,四分位间距=0.3 - 1.32),无晶状体眼组的视力为0.89±0.56(中位数=0.86,四分位间距=0.50 - 1.24)(P>0.05)。无晶状体眼组年龄与视觉效果之间存在正相关(r = 0.4,P = 0.04),而二期IOL组则无(P = 0.48)。二期IOL组平均近视漂移(-5.28±1.06 D)与无晶状体眼组(-5.10±1.02 D)之间无显著差异(P>0.05)。二期IOL组因并发症进行再次手术的发生率高于无晶状体眼组(分别为48%和16%,P≤0.01)。然而,在6个月以上的患者中,与无晶状体眼组相比,这种风险无显著差异。
尽管二期IOL植入治疗婴幼儿白内障在光学上可作为一种治疗选择,但与无晶状体眼相比,视觉效果无显著差异。6个月及以下患者因并发症进行再次手术的发生率高于无晶状体眼治疗的患者。