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[帕金森病的精神并发症:症状与治疗]

[Psychiatric complications of Parkinson's disease: their symptoms and treatment].

作者信息

Castro-García A, Sesar-Ignacio A, Ares-Pensado B

机构信息

Unidad de Trastornos del Movimiento, Hospital Clinico Universitario, Santiago de Compostela, Spain.

出版信息

Rev Neurol. 2004;39(7):646-50.

PMID:15490352
Abstract

INTRODUCTION AND DEVELOPMENT

Psychiatric symptoms in Parkinson's disease are relatively frequent, with a variation between 10 and 50%, according to different publications. They generally occur after several years of treatment. They may be symptoms derived from the disease itself or linked to the treatment used. These complications vary and include anxiety, affective and psychotic (hallucinations, delirium) disorders, as well as other alterations such as sexual, sleep and cognitive problems.

CONCLUSIONS

Treatment must always be tailor-made to suit each individual and in many cases we have to resort to lowering or withdrawing the dopaminergic medication while, in others, treatment with benzodiazepines, antidepressants and atypical neuroleptic drugs is indicated.

摘要

引言与发展

帕金森病中的精神症状相对常见,根据不同出版物,发生率在10%至50%之间。它们通常在治疗数年之后出现。这些症状可能源于疾病本身,也可能与所使用的治疗方法有关。这些并发症多种多样,包括焦虑、情感和精神性(幻觉、谵妄)障碍,以及其他改变,如性、睡眠和认知问题。

结论

治疗必须始终因人而异,在许多情况下,我们不得不减少或停用多巴胺能药物,而在其他情况下,则需使用苯二氮䓬类药物、抗抑郁药和非典型抗精神病药物进行治疗。

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