阻塞性睡眠呼吸暂停对用于冠状动脉病变评估的血流储备分数测量的影响。

The influence of obstructive sleep apnea on FFR measurements for coronary lesion assessment.

作者信息

Ciaramita Jeffrey P, Parham Walter A, Herrmann Steven, Khoukaz Souheil, Kern Morton J

机构信息

J. Gerard Mudd Cardiac Catheterization Laboratory, St. Louis University Health Sciences Center, 3635 Vista Avenue at Grand Boulevard, St. Louis, MO 63110, USA.

出版信息

J Interv Cardiol. 2004 Oct;17(5):331-7. doi: 10.1111/j.1540-8183.2004.04025.x.

DOI:10.1111/j.1540-8183.2004.04025.x

PMID:15491338

Abstract

Fractional flow reserve (FFR) determinations have been demonstrated to be largely independent of changes in systemic hemodynamic changes. Herein, we describe a case of obstructive sleep apnea cyclically altering FFR measurements from normal to abnormal in a patient with an intermediately severe coronary narrowing following treatment for an acute coronary syndrome. To eliminate uncertainty, FFR measurements should be made if possible during suspended respiration.

摘要

血流储备分数（FFR）测定已被证明在很大程度上独立于全身血流动力学变化。在此，我们描述了一例阻塞性睡眠呼吸暂停患者，在急性冠状动脉综合征治疗后，其冠状动脉中度狭窄，FFR测量值周期性地从正常变为异常。为消除不确定性，应尽可能在呼吸暂停期间进行FFR测量。