Morra Sofia, Roubille François
a Department of Cardiology , University Hospital of Montpellier , Montpellier , France.
b Department of Cardiac, Thoracic and Cardiovascular Sciences , University of Padua Medical School , Padua , Italy.
Acta Cardiol. 2018 Aug;73(4):319-324. doi: 10.1080/00015385.2017.1384183. Epub 2017 Oct 9.
Obstructive sleep apnoea (OSA) is an emerging and independent risk factor for cardiovascular diseases; coronary artery disease (CAD) is higher in OSA patients, even in the absence of other traditional cardiovascular risk factors. There is little evidence to show abnormalities in coronary blood flow (CBF) and disorders in coronary vascular resistance (CVR), occurring during the obstructive respiratory event, suggesting coronary microvascular dysfunction (CMD) as a potential mechanism of ischaemic heart disease (IHD) OSA-as a related consequence.
阻塞性睡眠呼吸暂停（OSA）是心血管疾病新出现的独立危险因素；即使在没有其他传统心血管危险因素的情况下，OSA患者患冠状动脉疾病（CAD）的几率也更高。几乎没有证据表明在阻塞性呼吸事件期间会出现冠状动脉血流（CBF）异常和冠状动脉血管阻力（CVR）紊乱，提示冠状动脉微血管功能障碍（CMD）是缺血性心脏病（IHD）相关后果——OSA的潜在机制。
