Sweet综合征与宫颈癌的罕见关联。
A rare association of Sweet's syndrome with cervical cancer.
作者信息
Culp L, Crowder S, Hatch S
机构信息
Department of Radiation Oncology, University of Texas Medical Branch, Galveston, TX 77555-0711, USA.
出版信息
Gynecol Oncol. 2004 Nov;95(2):396-9. doi: 10.1016/j.ygyno.2004.06.050.
BACKGROUND
Approximately 10-20% of patients with Sweet's syndrome have an associated malignancy. To our knowledge, Sweet's syndrome has been reported in cervical cancer in only three other patients.
CASE
We report a case of a 44-year-old female diagnosed with cervical cancer (FIGO IIIB), treated with concurrent chemotherapy and radiation therapy. Approximately 5 months after completing treatment, she presented with nausea, vomiting, and bullous pustular lesions on the hand. She was found to have a small bowel obstruction due to recurrence of her cervical cancer, and a biopsy of the skin lesion showed a marked dermal neutrophilic infiltrate consistent with Sweet's syndrome.
CONCLUSION
We report a case of Sweet's syndrome associated with cervical cancer, which is a rare finding.
背景
约10%-20%的Sweet综合征患者伴有恶性肿瘤。据我们所知，仅有另外3例宫颈癌患者被报道患有Sweet综合征。
病例
我们报告1例44岁女性，被诊断为宫颈癌（国际妇产科联盟IIIB期），接受同步放化疗。完成治疗约5个月后，她出现恶心、呕吐，手部出现大疱性脓疱性皮损。她被发现因宫颈癌复发导致小肠梗阻，皮肤病变活检显示真皮层有明显嗜中性粒细胞浸润，符合Sweet综合征。
结论
我们报告1例与宫颈癌相关的Sweet综合征病例，这是一个罕见的发现。
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