Chen Hsin-Chi, Kadono Takafumi, Mimura Yoshihiro, Saeki Hidehisa, Tamaki Kunihiko
Department of Dermatology, Faculty of Medicine, University of Tokyo, Tokyo, Japan.
J Dermatol. 2004 Jul;31(7):556-9. doi: 10.1111/j.1346-8138.2004.tb00554.x.
High-frequency ultrasound diagnostic equipment (HFUS) using probes with frequencies above 15-MHz has been utilized conventionally in preoperative assessments and postoperative follow-up of skin tumors. The advent of probes with even higher frequencies (up to 30-MHz) has widened the clinical applications of HFUS to inflammatory dermatoses which are histologically confined to the epidermis and upper dermis, such as psoriasis and atopic dermatitis. Ultrasound imaging has the advantage of being a noninvasive and relatively inexpensive technology that is quick and easy to perform. In addition, information obtained from HFUS is unique and useful for clinical diagnosis and evaluation for various skin disorders. We believe that HFUS has the potential to become a powerful tool for either clinical or investigative dermatology. Herein, we present a case of lichen sclerosus et atrophicus (LSA) to which we applied HFUS before skin biopsy and obtained substantial information for the differential diagnosis from morphea, and we reemphasize the usefulness of HFUS in studying the inflammatory skin disorders.
高频超声诊断设备(HFUS)使用频率高于15兆赫兹的探头,传统上已用于皮肤肿瘤的术前评估和术后随访。频率更高(高达30兆赫兹)的探头的出现,将HFUS的临床应用扩展到了组织学上局限于表皮和真皮上层的炎症性皮肤病,如银屑病和特应性皮炎。超声成像具有无创、相对廉价、操作快速简便的优点。此外,从HFUS获得的信息独特,对各种皮肤疾病的临床诊断和评估有用。我们认为HFUS有潜力成为临床或研究性皮肤病学的有力工具。在此,我们报告一例硬化萎缩性苔藓(LSA)病例,在皮肤活检前应用HFUS,获得了与硬斑病鉴别诊断的大量信息,并再次强调HFUS在研究炎症性皮肤病中的有用性。