Rose Amy E, Boyd Kevin P, Meehan Shane A, Latkowski Jo-Ann
New York University School of Medicine.
Dermatol Online J. 2013 Dec 16;19(12):20714.
Morphea and lichen sclerosus et atrophicus (LSA) have similar clinical presentations. Reports of patients with overlapping clinical and histopathologic features of both conditions have led some to speculate that they may represent different presentations along the same disease spectrum. It has been postulated that there is a common etiologic agent, which may involve autoimmunity, response to trauma, or infection. The link between Borrelia infection and both morphea and LSA has been widely studied but remains controversial. We present a case of a patient with lesions characterized by overlapping features of morphea and LSA with rapid decrease in joint mobility.
硬斑病和萎缩性硬化性苔藓(LSA)具有相似的临床表现。关于同时具有这两种疾病重叠临床和组织病理学特征患者的报告,使得一些人推测它们可能是同一疾病谱的不同表现形式。据推测存在一种共同的病因,可能涉及自身免疫、对创伤的反应或感染。莱姆病感染与硬斑病和LSA之间的联系已得到广泛研究,但仍存在争议。我们报告一例患者,其病变具有硬斑病和LSA的重叠特征,并伴有关节活动度迅速下降。