婴儿虹膜海绵状血管瘤。

Cavernous hemangioma of the iris in an infant.

作者信息

Woo Se Joon, Kim Chong Jai, Yu Young Suk

机构信息

Department of Ophthalmology, Seoul National University College of Medicine and Clinical Research Institute, Seoul National University Hospital, Korea.

出版信息

J AAPOS. 2004 Oct;8(5):499-501. doi: 10.1016/j.jaapos.2004.06.003.

DOI:10.1016/j.jaapos.2004.06.003

PMID:15492746

Abstract

Iris hemangioma is a rare intraocular tumor which can present with spontaneous hyphema. Juvenile xanthogranuloma, malignant melanoma with proliferation of vessels or hemorrhages in the region of cystic degeneration, and inflammatory granulomas are frequently confused with the true hemangiomas. Some authors have even questioned the very existence of iris hemangioma. Clinical case reports of iris hemangiomas with histopathologic evidence and clinical course after surgery are uncommon. We could not find any reports of iris vascular tumors confirmed using immunohistochemical staining with vascular markers. We report a case of a cavernous hemangioma of the iris in a 3-month-old infant treated surgically, and the histopathological findings and immunohistochemical analysis with vascular markers (factor VIII and CD34) are also shown.

摘要

虹膜血管瘤是一种罕见的眼内肿瘤，可表现为自发性前房积血。青少年黄色肉芽肿、囊性变性区域有血管增生或出血的恶性黑色素瘤以及炎性肉芽肿常与真正的血管瘤相混淆。一些作者甚至质疑虹膜血管瘤是否真的存在。有组织病理学证据及术后临床病程的虹膜血管瘤临床病例报告并不常见。我们未发现使用血管标志物进行免疫组化染色确诊的虹膜血管肿瘤的任何报告。我们报告了一例3个月大婴儿的虹膜海绵状血管瘤的手术治疗病例，并展示了其组织病理学发现及使用血管标志物（因子VIII和CD34）的免疫组化分析结果。