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原发性卵巢癌肉瘤:一例病例报告及文献综述

Primary ovarian carcinosarcoma: a case report and review of the literature.

作者信息

Varras M, Akrivis Ch, Antoniou N, Tolis C, Stefanaki S, Salamalekis E

机构信息

3rd Department of Obstetrics and Gynaecology, University General Hospital ATTIKON, Athens, Third District National Health System, Athens (Greece).

出版信息

Eur J Gynaecol Oncol. 2004;25(5):653-6.

Abstract

Primary ovarian carcinosarcoma is characterized by an admixture of malignant epithelial and stromal elements. This neoplasm is extremely rare with fewer than 400 cases reported in the English literature. Its histogenesis, clinical features and optimal treatment remain unclear because of the rarity of primary ovarian carcinosarcoma. This study focuses on the clinical, pathological, immunohistochemical features and survival of a 73-year-old patient with primary ovarian carcinocarcoma. The patient was treated with surgery followed by combined chemotherapy with carboplatin and taxol and assigned to FIGO Stage IIIc. She died from the disease 17 months after surgery. In conclusion, ovarian carcinosarcoma is a very aggressive tumor, especially when it is diagnosed at advanced stage.

摘要

原发性卵巢癌肉瘤的特征是恶性上皮和间质成分混合存在。这种肿瘤极为罕见,英文文献报道的病例不足400例。由于原发性卵巢癌肉瘤罕见,其组织发生、临床特征及最佳治疗方法仍不明确。本研究聚焦于一名73岁原发性卵巢癌肉瘤患者的临床、病理、免疫组化特征及生存情况。该患者接受了手术治疗,随后采用卡铂和紫杉醇联合化疗,分期为国际妇产科联盟(FIGO)IIIc期。她在术后17个月死于该疾病。总之,卵巢癌肉瘤是一种侵袭性很强的肿瘤,尤其是在晚期被诊断出来时。

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