Medical Microbiology Laboratory, Department of Microbiology, School of Life Sciences, Bharathidasan University, Tiruchirappalli, Tamilnadu, India.
BMC Cancer. 2011 Jun 3;11:218. doi: 10.1186/1471-2407-11-218.
Composing of less than 1% of all ovarian cancers, immature teratoma is a malignancy that mainly affects the young, and they present with advanced disease. The treatment of immature teratoma is conservative primary surgery usually involving unilateral salpingo-oophorectomy followed by combination chemotherapy.
Here we present a case of a 68 year old woman with bilateral ovarian teratoma complicated with carcinosarcoma. The patient was diagnosed as FIGO stage IIIC. She underwent neoadjuvant chemotherapy and interval cytoreduction followed by optimal cytoreduction. The post operative management strategies and gynaecological follow up studies revealed no evidence of regional or distant metastasis.
Thus the choice of initial treatment should be decided in a selective fashion depending on various prognostic factors in order to increase the survival of the patients.
不成熟畸胎瘤构成所有卵巢癌的不到 1%,是一种主要影响年轻人的恶性肿瘤,且其表现为晚期疾病。不成熟畸胎瘤的治疗方法为保守的初级手术,通常涉及单侧输卵管卵巢切除术,然后进行联合化疗。
这里我们报告了一例 68 岁女性,双侧卵巢畸胎瘤合并癌肉瘤。患者被诊断为 FIGO 分期 IIIIC 期。她接受了新辅助化疗和间隔性肿瘤细胞减灭术,然后进行了最佳肿瘤细胞减灭术。术后管理策略和妇科随访研究未发现局部或远处转移的证据。
因此,初始治疗的选择应根据各种预后因素进行选择性决定,以提高患者的生存率。