Martineau Pierre, Frenette Marc, Blais Lucie, Sauvé Claude
Hôpital du Sacré-Coeur de Montréal and Faculté de Pharmacie, Université de Montréal, Montréal, Québec, Canada.
Can J Cardiol. 2004 Oct;20(12):1205-11.
Life-saving drugs, such as angiotensin-converting enzyme inhibitors and beta-blockers, are frequently underused and underdosed in patients with heart failure. Specialized clinics have been shown to provide additional benefits.
To determine the impact of a multidisciplinary outpatient heart failure clinic on the frequency of cardiovascular readmissions and emergency room (ER) visits, length of inpatient and ER stays, and New York Heart Association (NYHA) class.
A retrospective chart review study comprising 72 patients who had two or more visits to a heart failure clinic between December 1, 1998, and August 31, 1999, was performed. The number of readmissions and ER visits, and the NYHA class were recorded during the six-month period before and after the first visit to the clinic.
Most subjects were in NYHA class III or IV (71% and 21%, respectively), and the mean ejection fraction was 31%. The post- versus preintervention relative risk of readmission was 0.43 (95% CI 0.25 to 0.72). The total number of inpatient days decreased by 54% (95% CI 44% to 62%). The post- versus preintervention relative risk of an ER visit was 0.29 (95% CI 0.19 to 0.45). The number of ER days decreased by 60% (95% CI 41% to 73%). NYHA functional class significantly improved, with most subjects ending the six-month postintervention period in class I or II (33% and 49%, respectively; P=0.001).
This multidisciplinary heart failure clinic significantly decreased the risk of cardiovascular readmissions and subsequent ER visits. It led to improvement in NYHA class and to a decrease in the number of days spent in the hospital and in the ER.
诸如血管紧张素转换酶抑制剂和β受体阻滞剂等救命药物在心力衰竭患者中经常未得到充分使用且剂量不足。已证明专科诊所能带来额外益处。
确定多学科门诊心力衰竭诊所对心血管疾病再入院频率和急诊室就诊次数、住院和急诊室停留时间以及纽约心脏协会(NYHA)分级的影响。
进行了一项回顾性图表审查研究,纳入了1998年12月1日至1999年8月31日期间到心力衰竭诊所就诊两次或更多次的72例患者。记录首次就诊诊所前后六个月期间的再入院和急诊室就诊次数以及NYHA分级。
大多数受试者为NYHAⅢ级或Ⅳ级(分别为71%和21%),平均射血分数为31%。干预后与干预前相比,再入院的相对风险为0.43(95%可信区间0.25至0.72)。住院总天数减少了54%(95%可信区间44%至62%)。干预后与干预前相比,急诊室就诊的相对风险为0.29(95%可信区间0.19至0.45)。急诊室停留天数减少了60%(95%可信区间41%至73%)。NYHA功能分级显著改善,大多数受试者在干预后六个月结束时为Ⅰ级或Ⅱ级(分别为33%和49%;P = 0.001)。
这个多学科心力衰竭诊所显著降低了心血管疾病再入院及随后急诊室就诊的风险。它使NYHA分级得到改善,并减少了在医院和急诊室的停留天数。