Hanley Marisol A, Jensen Mark P, Ehde Dawn M, Hoffman Amy J, Patterson David R, Robinson Lawrence R
Department of Rehabilitation Medicine, University of Washington School of Medicine, Seattle, Washington 98195-6490, USA.
Disabil Rehabil. 2004;26(14-15):882-93. doi: 10.1080/09638280410001708896.
To evaluate the utility of a biopsychosocial model to predict long-term adjustment to lower-limb amputation and phantom limb pain (PLP).
One month after lower-limb amputation, 70 participants completed measures of PLP intensity, cognitions (catastrophizing, perceived control over pain), coping (pain-contingent rest), social environment (social support, solicitous responding), and functioning (pain interference, depressive symptoms). The measures of functioning were administered again at 1- and 2-years post-amputation. Multiple regression analyses were used to examine the ability of the psychosocial variables at 1-month post-amputation to predict changes in the functioning measures over time.
The psychosocial variables at 1-month post-amputation, controlling for initial PLP intensity, accounted for 21% of the variance in change in depressive symptoms at 1-year (p < 0.05), and 27% and 22% (p's < 0.01 and 0.05, respectively) of the variance in change in pain interference and depressive symptoms, respectively, at 2-years post-amputation. Catastrophizing and social support were associated with decreases (improvement) in both criterion measures, while solicitous responding was associated with increases (worsening) in both measures.
The findings support a biopsychosocial model of long-term adjustment to amputation and PLP. In addition, results suggest that some psychosocial variables are more important than others for predicting adjustment, providing important implications for early interventions after amputation.
评估生物心理社会模型在预测下肢截肢及幻肢痛(PLP)长期适应情况方面的效用。
下肢截肢术后1个月,70名参与者完成了关于PLP强度、认知(灾难化思维、对疼痛的感知控制)、应对方式(因疼痛而休息)、社会环境(社会支持、过度关心的反应)及功能状况(疼痛干扰、抑郁症状)的测量。在截肢术后1年和2年时再次进行功能状况测量。采用多元回归分析来检验截肢术后1个月时心理社会变量预测功能状况测量指标随时间变化的能力。
截肢术后1个月时的心理社会变量,在控制初始PLP强度后,解释了1年时抑郁症状变化方差的21%(p < 0.05),以及截肢术后2年时疼痛干扰变化方差的27%和抑郁症状变化方差的22%(p值分别< 0.01和0.05)。灾难化思维和社会支持与两项标准测量指标的下降(改善)相关,而过度关心的反应与两项指标的上升(恶化)相关。
研究结果支持截肢及PLP长期适应的生物心理社会模型。此外,结果表明某些心理社会变量在预测适应方面比其他变量更重要,这为截肢后的早期干预提供了重要启示。