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三年后的PROGRESS试验：是时候进行一份关于疗效的平衡报告了。

The PROGRESS trial three years later: time for a balanced report of effectiveness.

作者信息

Wennberg Richard, Zimmermann Camilla

机构信息

Department of Medicine, University of Toronto, University Health Network, Toronto, ON, Canada M5T 2S8.

出版信息

BMJ. 2004 Oct 23;329(7472):968-70. doi: 10.1136/bmj.329.7472.968.

DOI:10.1136/bmj.329.7472.968
PMID:15499116
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC524114/
Abstract

Has the use of the phrase “perindopril based blood pressure lowering regimen” resulted in an oversimplistic and hence inaccurate interpretation of the results of the PROGRESS trial creeping into the literature and clinical practice?

摘要

“培哚普利降压方案”这一表述的使用是否导致了对PROGRESS试验结果过于简单化从而不准确的解读渗入到文献和临床实践中？

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本文引用的文献

1
Effects of a perindopril-based blood pressure-lowering regimen on the risk of recurrent stroke according to stroke subtype and medical history: the PROGRESS Trial.根据中风亚型和病史，培哚普利降压方案对复发性中风风险的影响：PROGRESS试验
Stroke. 2004 Jan;35(1):116-21. doi: 10.1161/01.STR.0000106480.76217.6F. Epub 2003 Dec 11.
2
Effects of different blood-pressure-lowering regimens on major cardiovascular events: results of prospectively-designed overviews of randomised trials.不同降压方案对主要心血管事件的影响：前瞻性设计的随机试验综述结果
Lancet. 2003 Nov 8;362(9395):1527-35. doi: 10.1016/s0140-6736(03)14739-3.
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Effects of a perindopril-based blood pressure-lowering regimen on disability and dependency in 6105 patients with cerebrovascular disease: a randomized controlled trial.基于培哚普利的降压方案对6105例脑血管疾病患者残疾和依赖状况的影响：一项随机对照试验
Stroke. 2003 Oct;34(10):2333-8. doi: 10.1161/01.STR.0000091397.81767.40. Epub 2003 Sep 4.
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Making PROGRESS in stable patients post stroke or transient ischaemic attack: implications for general practice.
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Effects of blood pressure lowering with perindopril and indapamide therapy on dementia and cognitive decline in patients with cerebrovascular disease.培哚普利和吲达帕胺降压治疗对脑血管疾病患者痴呆和认知功能减退的影响。
Arch Intern Med. 2003 May 12;163(9):1069-75. doi: 10.1001/archinte.163.9.1069.
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