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[妊娠急性脂肪肝]

[Acute fatty liver of pregnancy].

作者信息

Dieterle S, Niesert S, Schneider J

机构信息

Frauenklinik der Medizinischen Hochschule Hannover.

出版信息

Z Geburtshilfe Perinatol. 1992 Jan-Feb;196(1):41-3.

PMID:1549919
Abstract

Liver diseases in pregnancy can occur as a complication of gestation or independently. Acute fatty liver of pregnancy is a rare disease of unknown etiology specifically associated to gestation. The frequency is increased in the first pregnancy, in the last trimester and in multiple pregnancies. Because of the high maternal and perinatal mortality early diagnosis is necessary for prompt termination of pregnancy. This case report is intended to facilitate the differentiation between acute fatty liver of pregnancy and other liver diseases in pregnancy. The differential diagnoses include preeclampsia, HELLP syndrome, intrahepatic cholestasis of pregnancy and acute viral hepatitis.

摘要

妊娠期肝病可作为妊娠并发症出现,也可独立发生。妊娠急性脂肪肝是一种病因不明的罕见疾病,与妊娠密切相关。初产妇、妊娠晚期及多胎妊娠时其发病率会增加。由于孕产妇和围产儿死亡率高,早期诊断对于及时终止妊娠很有必要。本病例报告旨在促进妊娠急性脂肪肝与其他妊娠期肝病的鉴别诊断。鉴别诊断包括子痫前期、HELLP综合征、妊娠期肝内胆汁淤积症和急性病毒性肝炎。

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