Maetzel F K, Glocke M H, Jungmann H, Klein B, Teilken M
Curschmann-Klinik, Timmendorfer Strand.
Z Kardiol. 1992 Feb;81(2):99-109.
In 50 patients with coronary heart disease (CHD), 44 of them with a recent history of myocardial infarction, 2 tests on the bicycle-ergometer in the supine position, one with the crankshaft on the level of the examination cot and one with an elevation of the pedal axle by 30 cm were carried out within 30-minute intervals after initiating a flow directed right heart catheterization. In chronological sequence of the recruitment the patients began the ergometric tests alternately with a low or an elevated crank. The applied exercise loads of 50 and 75 watts lasted 3 minutes each. The results show clinically relevant differences between the 2 positions of the pedal axle, being in many cases statistically significant (p less than or equal to 0.01). The pressure of the pulmonary artery (PAP) was elevated at rest and under exercise load when the pedal axle was elevated. The changes of the pressure of the pulmonary artery through the exercise load are greater in patients with an impaired left ventricular function at rest with both pedal axle positions than in patients with a normal left ventricular function. We observed under increasing exercise load a diverging more pronounced elevation of PAP-curves only as a trend in the group of patients with an impaired left ventricular function. Heart rate and systolic blood pressure were on average likewise higher with the elevated crank then with the low one, however the mean variations were considerable. The oxygen saturation of the blood was somewhat less at rest and during exercise load when the pedal axle was elevated compared to the findings with the low pedal axle. The decrease of the oxygen saturation under exercise load was most pronounced in patients having already at rest an impaired left ventricular function. However, with both positions of the pedal axle the behaviour was identical.
在50例冠心病(CHD)患者中,其中44例有近期心肌梗死病史,在开始进行血流导向右心导管检查后的30分钟内,于仰卧位在自行车测力计上进行了2次测试,一次是曲轴位于检查床水平,另一次是踏板轴抬高30厘米。按照招募的时间顺序,患者交替以低曲轴或高曲轴开始测力计测试。所施加的50瓦和75瓦运动负荷各持续3分钟。结果显示踏板轴的2个位置之间存在临床相关差异,在许多情况下具有统计学意义(p≤0.01)。当踏板轴抬高时,静息和运动负荷下肺动脉压力(PAP)升高。在静息时左心室功能受损的患者中,无论踏板轴处于何种位置,运动负荷引起的肺动脉压力变化都比左心室功能正常的患者更大。在左心室功能受损的患者组中,随着运动负荷增加,我们仅观察到PAP曲线有更明显的不同升高趋势。平均而言,高曲轴时的心率和收缩压同样高于低曲轴时,但平均变化幅度较大。与低踏板轴时的结果相比,当踏板轴抬高时,静息和运动负荷期间血液的氧饱和度略低。运动负荷下氧饱和度的下降在静息时左心室功能已受损的患者中最为明显。然而,踏板轴的2个位置的情况相同。