Kong Michael S, Harford Robert, O'Neill Jennifer T
Regional Support Organization, San Diego, California 92136, USA.
Cutis. 2004 Sep;74(3):173-9.
Keratosis punctata palmoplantaris (KPPP) is a rare genodermatosis with an autosomal-dominant pattern of inheritance. We report the case of a 61-year-old woman who presented with a long history of multiple symptomatic hyperkeratotic papules on the palms and soles. In addition, we review the literature and present the current classification of the heterogeneous group of punctate palmoplantar keratoses, the cutaneous and histologic findings, the differential diagnosis, the possible association with various anomalies including malignancies, and the various treatment options.
掌跖点状角化病（KPPP）是一种罕见的遗传性皮肤病，呈常染色体显性遗传模式。我们报告了一例61岁女性病例，该患者手掌和脚底出现多个有症状的角化过度丘疹，病史较长。此外，我们回顾了文献，并介绍了点状掌跖角化病这一异质性疾病组的当前分类、皮肤和组织学表现、鉴别诊断、与包括恶性肿瘤在内的各种异常情况的可能关联以及各种治疗选择。
