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替代性社交经历对雄性小鼠性功能的影响。

Effects of alternative social experience on the sexual function of male mice.

作者信息

Amikishieva A V, Ovsyukova M V

机构信息

Institute of Cytology and Genetics, Novosibirsk.

出版信息

Bull Exp Biol Med. 2003 Dec;136(6):607-10. doi: 10.1023/b:bebm.0000020217.37770.42.

DOI:10.1023/b:bebm.0000020217.37770.42
PMID:15500085
Abstract

The relevance of the social contact test "Wall" for evaluation of sexual motivation of male mice was tested and confirmed. Motivation of C57BL/6J male mice with alternative social experience (winners and victims in 10 and 20 daily male-male confrontations) was evaluated. Elevated primary sexual interest was detected in aggressive animals after 10 confrontations, while in submissive animals this interest was decreased; however after 20 confrontations sexual motivation in both groups was characterized by rapid exhaustion and low basal level of testosterone. Hence, the sexual function of male mice is inhibited under conditions of long social conflicts irrespective of previous experience of victories or defeats in male-male confrontations.

摘要

对用于评估雄性小鼠性动机的社交接触测试“墙”的相关性进行了测试并得到证实。评估了具有不同社交经历(在每日10次和20次雄-雄对抗中分别为胜利者和受害者)的C57BL/6J雄性小鼠的动机。在10次对抗后,在具有攻击性的动物中检测到原发性性兴趣升高,而在顺从性动物中这种兴趣降低;然而,在20次对抗后,两组的性动机均表现为快速耗尽且睾酮基础水平较低。因此,无论在雄-雄对抗中先前的胜利或失败经历如何,在长期社会冲突的条件下雄性小鼠的性功能都会受到抑制。

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