Orengo Claudia A, Fullerton Ginny, Tan Robert
Department of psychiatry and behavioral sciences, Baylor College of Medicine, Mental Health Care Line, Veterans Affairs Medical Center, Houston, TX, USA.
Geriatrics. 2004 Oct;59(10):24-30.
Depression, which affects approximately 6 million men in the United States, is associated with a high risk of mortality from comorbid medical illnesses and from suicide. Evidence suggests that depresssion affects men differently than women, and that older men in particular may experience special influences, symptoms, and consequences. The causes of late life depression can be divided into psychological, social, and biological factors. Special considerations for this population include laboratory studies to identify possible secondary medical abnormalities that may either accompany or derive from the depressed mood, and pharmacologic treatments that have been shown to be more efficacious in aging men. Research involving depressed hypogonadal and eugonadal men suggests that depressed men may benefit from testosterone augmentation.
在美国，约有600万男性受抑郁症影响，抑郁症与因合并症及自杀导致的高死亡风险相关。有证据表明，抑郁症对男性的影响与女性不同，尤其是老年男性可能会受到特殊影响、出现特殊症状并产生特殊后果。晚年抑郁症的病因可分为心理、社会和生物因素。针对这一人群的特殊考量包括进行实验室研究，以识别可能伴随抑郁情绪或由抑郁情绪引发的继发性医学异常情况，以及使用已被证明对老年男性更有效的药物治疗。涉及性腺功能减退和性腺功能正常的抑郁症男性的研究表明，抑郁症男性可能会从睾酮补充中获益。
