Douville E Charles, Asaph James W, Dworkin Ronald J, Handy John R, Canepa Clifford S, Grunkemeier Gary L, Wu YingXing
Division of Cardiothoracic Surgery, The Oregon Clinic PC, Portland, Oregon 97213, USA.
Ann Thorac Surg. 2004 Nov;78(5):1659-64. doi: 10.1016/j.athoracsur.2004.04.082.
Postcardiotomy sternal wound complications remain challenging. The prevailing approach for deep sternal wound infection of debridement and flap coverage without osseous closure makes subsequent reoperation difficult.
An analysis of all patients undergoing cardiac surgery at a single institution between 1986 and 2001 was conducted. Prospective data collection and chart review were used to compare different treatment strategies for sternal complications.
Of 5337 patients, 122 had sternal wound complications (2.2%) comprising 15 (0.3%) uninfected dehiscences (El Oakley class 1), 45 (0.8%) superficial infections (El Oakley class 2A), and 62 (1.1%) deep sternal wound infections (El Oakley class 2B). Thirty-two patients with deep sternal infection were treated by debridement, rewiring, and delayed primary closure. There were initial treatment failures in 6 patients (18.8%) and ultimate failures in 2 patients (6.3%), both of whom died. One of these patients had previously received external beam radiation after a radical mastectomy for breast cancer. Median length of stay was 32 days and median time to wound healing was 85 days. Twenty-five patients were managed by muscle flap coverage without sternal reclosure. There were 6 initial treatment failures (24%) but no ultimate failures or deaths (p = NS). Median length of stay was 31 days and median infection time was 161 days.
In patients with postcardiotomy deep sternal wound infection without previous chest radiation, debridement, rewiring, and delayed skin closure is effective. It offers a shorter healing time and probably makes late cardiac reoperation safer. We propose an algorithm for the management of poststernotomy complications.
心脏手术后胸骨伤口并发症仍然具有挑战性。目前对于深部胸骨伤口感染采用清创和皮瓣覆盖而不进行骨性闭合的方法,使得后续再次手术困难。
对1986年至2001年间在单一机构接受心脏手术的所有患者进行分析。采用前瞻性数据收集和病历审查来比较胸骨并发症的不同治疗策略。
在5337例患者中,122例出现胸骨伤口并发症(2.2%),包括15例(0.3%)未感染的胸骨裂开(埃尔奥克利1级)、45例(0.8%)表浅感染(埃尔奥克利2A级)和62例(1.1%)深部胸骨伤口感染(埃尔奥克利2B级)。32例深部胸骨感染患者接受了清创、重新固定钢丝和延迟一期缝合治疗。6例患者(18.8%)出现初始治疗失败,2例患者(6.3%)最终治疗失败,这2例患者均死亡。其中1例患者此前因乳腺癌根治性乳房切除术后接受了外照射放疗。中位住院时间为32天,伤口愈合的中位时间为85天。25例患者采用肌皮瓣覆盖而未进行胸骨重新闭合处理。有6例初始治疗失败(24%),但无最终治疗失败或死亡情况(p=无显著性差异)。中位住院时间为31天,中位感染时间为161天。
对于心脏手术后深部胸骨伤口感染且既往未接受胸部放疗的患者,清创、重新固定钢丝和延迟皮肤闭合是有效的。它提供了更短的愈合时间,并且可能使后期心脏再次手术更安全。我们提出了一种胸骨切开术后并发症的处理方案。