Dursun Dilek, Akova Yonca A, Bilezikçi Banu
Department of Ophthalmology, Baskent University Medical School, Ankara, Turkey.
Ocul Immunol Inflamm. 2004 Jun;12(2):143-8. doi: 10.1080/09273940490895353.
To review scleritis cases associated with sarcoidosis and to evaluate clinical features, medical treatment, and clinical course.
Two cases of diffuse anterior scleritis and a nodular scleritis case associated with systemic sarcoidosis were evaluated. Scleritis was the first manifestation of sarcoidosis in two of the patients and the diagnosis of sarcoidosis was confirmed with a conjunctival biopsy. The third patient had the diagnosis of systemic sarcoidosis when she developed scleritis.
Based on the clinical and histological appearance, two patients presented with bilateral diffuse anterior scleritis and the third patient with an anterior nodular scleritis. One patient already had the diagnosis of systemic sarcoidosis at presentation, while ocular findings led to the diagnosis in the other two cases. Conjunctiva or skin biopsies revealed features compatible with the diagnosis of sarcoidosis. Scleritis attacks recurred in two patients. All patients responded well to systemic corticosteroid (prednisone) therapy.
Scleritis associated with sarcoidosis has rarely been described and it may be the presenting sign of systemic sarcoidosis.
回顾结节病相关的巩膜炎病例，并评估其临床特征、药物治疗及临床病程。
对两例弥漫性前巩膜炎及一例与系统性结节病相关的结节性巩膜炎病例进行评估。巩膜炎是其中两名患者结节病的首发表现，通过结膜活检确诊结节病。第三名患者在发生巩膜炎时已确诊为系统性结节病。
根据临床及组织学表现，两名患者表现为双侧弥漫性前巩膜炎，第三名患者表现为前结节性巩膜炎。一名患者就诊时已确诊为系统性结节病，而另外两例则通过眼部表现确诊。结膜或皮肤活检显示符合结节病诊断的特征。两名患者巩膜炎发作复发。所有患者对全身用皮质类固醇（泼尼松）治疗反应良好。
与结节病相关的巩膜炎鲜有报道，它可能是系统性结节病的首发体征。
