Wierzbowska Joanna, Stankiewicz Andrzej
Z Kliniki Okulistycznej Wojskowego Instytutu Medycznego w Warszawie.
Klin Oczna. 2004;106(3):352-9.
In the first part of the article the main information and recent research on the uveoscleral outflow pathway, including its morphology and physiology were presented. The structure of extracellular matrix of ciliary muscle and the changes of it, that are induced by prostaglandins, resulting in decreasing intraocular pressure were emphasized. In the second part biochemical characteristics of prostaglandin analogues, using nowadays were presented. Their efficacy in reducing intraocular pressure and safety profile were described.
在文章的第一部分,介绍了关于葡萄膜巩膜流出途径的主要信息和最新研究,包括其形态学和生理学。强调了睫状肌细胞外基质的结构及其由前列腺素诱导的变化,这些变化导致眼压降低。在第二部分,介绍了目前使用的前列腺素类似物的生化特性。描述了它们在降低眼压方面的功效和安全性。