Fenton J E, Chin R Y K, Fagan P A, Sterkers O, Sterkers J M
Departments of Otolaryngology/Neuro-otology, St. Vincent's Hospital, Sydney, Australia.
Acta Otorhinolaryngol Belg. 2004;58(2):103-7.
PROBLEMS/OBJECTIVES: Tumour size, intra-operative electrophysiologic thresholds and postoperative facial nerve function have been demonstrated to be important predictors of ultimate facial nerve function after vestibular schwannoma surgery. In general little attention has been given to the prediction of outcome of facial nerve function in non-vestibular schwannoma tumour surgery of the cerebellopontine angle (CPA).
A prospective study was performed to assess the predictive value of patient, tumour histology and electrophysiologic factors in the estimation of ultimate facial nerve outcome after this form of surgery.
Sixteen patients satisfied the requirements of the study. Poor long-term facial nerve outcome was associated with abnormal pre-operative facial nerve function, facial nerve schwannomas, premeatal meningiomas and electrophysiologic stimulation thresholds of greater than 0.1 mA.
It is concluded that tumour histology and pre-operative facial nerve function are additional factors that must be considered in the prediction of facial nerve function after non-vestibular schwannoma surgery of the CPA.
问题/目标:肿瘤大小、术中电生理阈值和术后面神经功能已被证明是前庭神经鞘瘤手术后最终面神经功能的重要预测指标。一般而言,对于桥小脑角(CPA)非前庭神经鞘瘤手术中面神经功能结果的预测关注较少。
进行了一项前瞻性研究,以评估患者、肿瘤组织学和电生理因素在这种手术形式后对最终面神经结果评估中的预测价值。
16名患者符合研究要求。长期面神经结果不佳与术前面神经功能异常、面神经鞘瘤、耳门前脑膜瘤以及大于0.1 mA的电生理刺激阈值有关。
得出结论,在CPA非前庭神经鞘瘤手术后预测面神经功能时,肿瘤组织学和术前面神经功能是必须考虑的额外因素。