Levin Ishai, Grisaru Dan, Pauzner David, Almog Benny
The Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Obstet Gynecol. 2004 Nov;104(5 Pt 2):1172-4. doi: 10.1097/01.AOG.0000128113.82312.34.
Trophoblastic tissue spread following uterine perforation during dilation and curettage is rare. We present a case of trophoblastic spread to the sigmoid colon following uterine perforation, which was treated by surgical removal of the implants and intramuscular administration of methotrexate.
A woman presented 3 weeks after curettage for a blighted ovum. Laparotomy performed for suspected intra-abdominal bleeding revealed bleeding trophoblastic implants in a perforation tract and the anterior uterine wall and on the appendix epiploica of the sigmoid colon. The implants were surgically removed and methotrexate was administered for persistently high beta-hCG levels. The patient fully recovered.
Extrauterine trophoblastic implants should be considered in women evaluated for abdominal pain whose pregnancy test is positive after uterine perforation. Conservative treatment with methotrexate in nonacute patients may be considered.
刮宫术中子宫穿孔后滋养层组织扩散罕见。我们报告一例子宫穿孔后滋养层扩散至乙状结肠的病例,该病例通过手术切除植入物并肌内注射甲氨蝶呤进行治疗。
一名女性在刮宫术后3周因稽留流产就诊。因怀疑腹腔内出血而行剖腹探查术,发现穿孔道、子宫前壁及乙状结肠网膜阑尾上有出血性滋养层植入物。手术切除植入物,并因β-人绒毛膜促性腺激素(β-hCG)水平持续升高而给予甲氨蝶呤治疗。患者完全康复。
对于子宫穿孔后妊娠试验阳性且因腹痛接受评估的女性,应考虑宫外滋养层植入物的可能。对于非急性患者,可考虑用甲氨蝶呤进行保守治疗。