Weckesser M, Könemann S, Brinkmann M, Willich N, Schober O
Klinik und Poliklinik für Nuklearmedizin, Universitätsklinikum Münster.
Radiologe. 2004 Nov;44(11):1096-104. doi: 10.1007/s00117-004-1124-7.
Combining positron emission tomography (PET) and X-ray computed tomography (CT) with simultaneous acquisition may improve diagnostic accuracy in oncology. Moreover this combination holds considerable promise in radiotherapy. Metabolic information may be used in decision making in radiotherapy and in planning target volumes. Furthermore early evaluation of treatment efficacy becomes possible. New tracers for the assessment of tumour hypoxia or apoptosis in clinical routine are currently being developed. These tracers may yield high relevance in radiotherapy. Hybrid scanners facilitate patient handling and shorten the duration of acquisition. Furthermore fusion accuracy is optimal. Prospective studies have to be conducted to show that the new technology improves patient care in terms of efficiency and quality.
将正电子发射断层扫描(PET)与X射线计算机断层扫描(CT)同时采集相结合,可能会提高肿瘤学的诊断准确性。此外,这种组合在放射治疗方面也有很大的前景。代谢信息可用于放射治疗的决策制定和靶区体积规划。此外,还可以对治疗效果进行早期评估。目前正在开发用于临床常规评估肿瘤缺氧或凋亡的新型示踪剂。这些示踪剂在放射治疗中可能具有高度相关性。混合型扫描仪便于患者管理并缩短采集时间。此外,融合精度是最佳的。必须进行前瞻性研究,以证明这项新技术在效率和质量方面改善了患者护理。