过期妊娠时脐动脉和大脑中动脉搏动指数及脑胎盘比的参考范围
Reference ranges for umbilical and middle cerebral artery pulsatility index and cerebroplacental ratio in prolonged pregnancies.
作者信息
Palacio M, Figueras F, Zamora L, Jiménez J M, Puerto B, Coll O, Cararach V, Vanrell J A
机构信息
Institut Clínic de Ginecologia, Obstetrícia i Neonatologia, Hospital Clínic de Barcelona, Barcelona, Spain.
出版信息
Ultrasound Obstet Gynecol. 2004 Nov;24(6):647-53. doi: 10.1002/uog.1761.
OBJECTIVE
To construct normal ranges for umbilical artery pulsatility index (UA PI), middle cerebral artery pulsatility index (MCA PI) and cerebroplacental ratio (CPR) in prolonged pregnancies according to strict methodological criteria using polynomial regression analysis.
METHODS
This was a retrospective, cross-sectional observational study involving 140 women, 10 women for each gestational day between 287 and 300 days of gestation. Fetal Doppler parameters were assessed to construct normal reference ranges for UA PI and MCA PI. CPR was calculated as a ratio of MCA PI/UA PI.
RESULTS
Mathematical modeling of the data demonstrated that the optimal fit was a linear polynomial one. Mean, 5th and 95th centiles were calculated for UA, MCA and CPR and centile curves from the regression analysis were constructed.
CONCLUSIONS
Reference ranges for UA PI, MCA PI and CPR in prolonged pregnancies have been constructed. MCA PI shows a wider range than previously reported in the literature.
目的
根据严格的方法学标准，采用多项式回归分析构建过期妊娠时脐动脉搏动指数（UA PI）、大脑中动脉搏动指数（MCA PI）和脑胎盘比率（CPR）的正常范围。
方法
这是一项回顾性横断面观察研究，涉及140名女性，妊娠287至300天期间，每天有10名女性。评估胎儿多普勒参数以构建UA PI和MCA PI的正常参考范围。CPR计算为MCA PI/UA PI的比值。
结果
数据的数学建模表明，最佳拟合为线性多项式。计算了UA、MCA和CPR的均值、第5和第95百分位数，并构建了回归分析的百分位数曲线。
结论
已构建过期妊娠时UA PI、MCA PI和CPR的参考范围。MCA PI显示出比文献中先前报道的更宽的范围。
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