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[晚期和复发性卵巢肿瘤及腹膜乳头状浆液性癌的细胞减灭术结果]

[Results of cytoreductive surgery for advanced and recurrent ovarian neoplasms and papillary serous carcinomas of the peritoneum].

作者信息

Ivanov S, Ivanov S

出版信息

Akush Ginekol (Sofiia). 2004;43(5):36-8.

Abstract

The aim of our study was to review and show the long-term results of the cytoreductive surgery in the treatment of advanced primary and recurrent epithelial ovarian cancers and papillary serous carcinomas of the peritoneum. We wanted to find clinical factors and in this way to select patients who can benefit from this kind of treatment. The clinical data of 32 patients searched retrospectively are presented in our research work. In 29 patients was possible radical cytoreductive surgery. Neoadjuvant and early postoperative chemotherapy were applied in most of the patients. The median follow up after cytoreductive surgery was 50 months. The overall median survival after cytoreduction was 38.5 months. We consider the cytoreductive surgery to be effective only when combined with neoadjuvant or with early postoperative chemotherapy. The surgical approach without chemotherapy leads to bad results.

摘要

我们研究的目的是回顾并展示减瘤手术治疗晚期原发性和复发性上皮性卵巢癌及腹膜乳头状浆液性癌的长期结果。我们希望找到临床因素,从而选择能从这类治疗中获益的患者。我们的研究工作呈现了对32例患者进行回顾性检索得到的临床数据。29例患者可行根治性减瘤手术。大多数患者接受了新辅助化疗和术后早期化疗。减瘤手术后的中位随访时间为50个月。减瘤后的总体中位生存期为38.5个月。我们认为减瘤手术只有在与新辅助化疗或术后早期化疗联合应用时才有效。不进行化疗的手术方式会导致不良结果。

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