Rajtar Renata, Malczewska-Malec Małgorzata, Kloch Małgorzata, Kolasińska-Kloch Władysława
II Klinika Kardiologii, Instytutu Kardiologii, Collegium Medicum, Uniwersytetu Jagiellońskiego w Krakowie.
Przegl Lek. 2004;61(3):165-9.
The theories formulated to explain atherogenesis evolved from vessel wall lipid to endothelial dysfunction with vascular wall remodelling. Chlamydia pneumoniae has been demonstrated to play an important role in the development of inflammatory and immunological process and can initiate atherogenesis. This pathogen is found in atherosclerotic plaques, which can induce complex activation of local inflammatory and immunological events and lead to the development of unstable plaque, vascular remodelling and vessel lumen constriction.
为解释动脉粥样硬化形成而提出的理论已从血管壁脂质学说发展到内皮功能障碍伴血管壁重塑学说。肺炎衣原体已被证明在炎症和免疫过程的发展中起重要作用，并可引发动脉粥样硬化形成。这种病原体存在于动脉粥样硬化斑块中，可诱导局部炎症和免疫事件的复杂激活，并导致不稳定斑块的形成、血管重塑和血管腔狭窄。
