Lenzenweger Mark F, Clarkin John F, Fertuck Eric A, Kernberg Otto F
Department of Psychology, Harvard University, USA.
J Pers Disord. 2004 Oct;18(5):421-38. doi: 10.1521/pedi.18.5.421.51323.
It is argued that borderline personality disorder (BPD) represents the interaction of underlying neurobehavioral systems that are reflected principally in the phenotypic constructs of positive emotion, negative emotion, and nonaffective constraint (Depue & Lenzenweger, 2001). This preliminary and exploratory study sought to examine predictions made from the Depue-Lenzenweger model with respect to controlled (effortful) information processing in BPD. It was hypothesized that (a) BPD subjects may display deficits on tasks that require controlled information processing (sustained attention, spatial working memory, and executive functioning), (b) they may reveal elevated negative emotion as well as decreased positive emotion and nonaffective constraint, and (c) nonaffective constraint should be substantially inversely associated with accurate performance on controlled information processing tasks. The results of this study, which examined 24 BPD diagnosed individuals and 68 normal adults, found support for each of these predictions in relation to performance on the Wisconsin Card Sorting Test. The implications of these results for further experimental psychopathology investigations of BPD as well as further refinement of theoretical models of the disorder are discussed.
有人认为，边缘型人格障碍（BPD）代表了潜在神经行为系统的相互作用，这种相互作用主要体现在积极情绪、消极情绪和非情感约束的表型结构中（德普伊和伦曾韦格，2001年）。这项初步的探索性研究旨在检验德普伊-伦曾韦格模型对边缘型人格障碍中受控（努力的）信息处理的预测。研究假设如下：（a）边缘型人格障碍患者在需要受控信息处理的任务（持续注意力、空间工作记忆和执行功能）上可能表现出缺陷；（b）他们可能表现出消极情绪升高，积极情绪和非情感约束降低；（c）非情感约束应与受控信息处理任务的准确表现呈显著负相关。这项研究对24名被诊断为边缘型人格障碍的个体和68名正常成年人进行了检查，结果发现这些预测在威斯康星卡片分类测验的表现方面都得到了支持。本文讨论了这些结果对边缘型人格障碍进一步实验性精神病理学研究以及该障碍理论模型进一步完善的意义。
