Cambon-Thomsen Anne
Institut National de la Santé et de la Recherche Médicale, Inserm U 558, Faculté de médecine, 37 allées Jules Guesde, F-31073 Toulouse Cedex, France.
Nat Rev Genet. 2004 Nov;5(11):866-73. doi: 10.1038/nrg1473.
Biobanking - the organized collection of biological samples and associated data - ranges in scope from small collections of samples in academic or hospital settings to large-scale national repositories. Biobanks raise many ethical concerns, to which authorities are responding by introducing specific regulations. Genomics research, which thrives on the sharing of samples and information, is affected by two prominent ethical questions: do ethical principles prevent or promote the sharing of stored biological resources? How does the advent of large-scale biobanking alter the way in which ethical issues are addressed?
生物样本库——生物样本及相关数据的有组织收集——其范围涵盖从学术机构或医院环境中的小型样本收集到大规模的国家储存库。生物样本库引发了诸多伦理问题,对此当局正在通过出台具体法规加以应对。依赖样本和信息共享而蓬勃发展的基因组学研究受到两个突出伦理问题的影响:伦理原则是阻碍还是促进储存生物资源的共享?大规模生物样本库的出现如何改变处理伦理问题的方式?