Pagano M E, Skodol A E, Stout R L, Shea M T, Yen S, Grilo C M, Sanislow C A, Bender D S, McGlashan T H, Zanarini M C, Gunderson J G
Department of Psychiatry and Human Behavior, Brown University Medical School, Providence, RI 02912, USA.
Acta Psychiatr Scand. 2004 Dec;110(6):421-9. doi: 10.1111/j.1600-0447.2004.00398.x.
Although much attention has been given to the effects of adverse childhood experiences on the development of personality disorders (PDs), we know far less about how recent life events influence the ongoing course of functioning. We examined the extent to which PD subjects differ in rates of life events and the extent to which life events impact psychosocial functioning.
A total of 633 subjects were drawn from the Collaborative Longitudinal Personality Disorders Study (CLPS), a multi-site study of four personality disorders--schizotypal (STPD), borderline (BPD), avoidant (AVPD), obsessive-compulsive (OCPD)--and a comparison group of major depressive disorders (MDD) without PD.
Borderline personality disorder subjects reported significantly more total negative life events than other PDs or subjects with MDD. Negative events, especially interpersonal events, predicted decreased psychosocial functioning over time.
Our findings indicate higher rates of negative events in subjects with more severe PDs and suggest that negative life events adversely impact multiple areas of psychosocial functioning.
尽管童年不良经历对人格障碍(PDs)发展的影响已受到广泛关注,但我们对近期生活事件如何影响持续的功能运作过程了解甚少。我们研究了人格障碍患者在生活事件发生率上的差异程度,以及生活事件对心理社会功能的影响程度。
共有633名受试者来自协作性纵向人格障碍研究(CLPS),这是一项针对四种人格障碍——分裂型(STPD)、边缘型(BPD)、回避型(AVPD)、强迫型(OCPD)——以及一组无人格障碍的重度抑郁症(MDD)对照组的多中心研究。
边缘型人格障碍患者报告的负面生活事件总数显著多于其他人格障碍患者或重度抑郁症患者。负面事件,尤其是人际事件,预示着随着时间推移心理社会功能会下降。
我们的研究结果表明,较严重人格障碍患者的负面事件发生率更高,并表明负面生活事件会对心理社会功能的多个方面产生不利影响。