双胞胎中的肾母细胞瘤、尿道下裂和隐睾症。
Wilm's tumour, hypospadias, and cryptorchidism in twins.
作者信息
Bond J V
出版信息
Arch Dis Child. 1977 Mar;52(3):243-5. doi: 10.1136/adc.52.3.243.
Abstract
Twin boys, both of whom had hypospadias and bilateral cryptorchidism, each developed a left-sided Wilms's tumour. The first twin was found to have an advanced multifocal tumour at the age of 15 months and died with local recurrence and pulmonary metastases. The diagnosis was made in the second twin one month later and at nephrectomy the tumour was found to be encapsulated without metastases; he is disease-free 12-years later. Although the histological appearances were similar in each twin, the tumours did not develop at the same rate and did not show the 'mirror-image' pattern suggested for embryonal tumours in identical twins.
摘要
一对双胞胎男孩，两人均患有尿道下裂和双侧隐睾症，各自都患上了左侧肾母细胞瘤。第一个双胞胎在15个月大时被发现患有晚期多灶性肿瘤，最终因局部复发和肺转移而死亡。一个月后在第二个双胞胎身上做出了诊断，肾切除时发现肿瘤有包膜且无转移；12年后他无病生存。尽管每个双胞胎的组织学表现相似，但肿瘤的发展速度不同，也未表现出同卵双胞胎胚胎肿瘤所提示的“镜像”模式。
相似文献
1
Wilm's tumour, hypospadias, and cryptorchidism in twins.双胞胎中的肾母细胞瘤、尿道下裂和隐睾症。
Arch Dis Child. 1977 Mar;52(3):243-5. doi: 10.1136/adc.52.3.243.
2
Bilateral Wilms' tumour. Age at diagnosis, associated congenital anormalies, and possible pattern of inheritance.
Lancet. 1975 Sep 13;2(7933):482-4. doi: 10.1016/s0140-6736(75)90550-4.
3
Letter: Bilateral Wilms' tumour and urinary-tract anomalies.
Lancet. 1975 Oct 11;2(7937):721. doi: 10.1016/s0140-6736(75)90834-x.
4
Wilms's tumour and aniridia: clinical and cytogenetic features.肾母细胞瘤与无虹膜：临床及细胞遗传学特征
Arch Dis Child. 1982 Sep;57(9):685-90. doi: 10.1136/adc.57.9.685.
5
Adult Wilms' tumor with hypospadias and cryptorchidism: a case report.成人肾母细胞瘤合并尿道下裂和隐睾症：一例报告
Kaohsiung J Med Sci. 2007 Nov;23(11):584-9. doi: 10.1111/j.2410-8650.2007.tb00002.x.
6
Bilateral Wilms tumor in a boy with severe hypospadias and cryptochidism due to a heterozygous mutation in the WT1 gene.一名患有严重尿道下裂和隐睾症的男孩因WT1基因杂合突变而患双侧肾母细胞瘤。
Pediatr Res. 1999 Feb;45(2):187-90. doi: 10.1203/00006450-199902000-00005.
7
Familial occurrence of Wilms' tumor: nephroblastoma in one of monozygous twins and in another sibling.肾母细胞瘤的家族性发病情况：单卵双胞胎之一及另一个同胞患肾母细胞瘤。
Am J Hum Genet. 1975 Mar;27(2):155-64.
8
Proceedings of the Tumor Board of the Children's Hospital of Philadelphia: bilateral Wilms tumor.
Med Pediatr Oncol. 1979;7(2):191-5. doi: 10.1002/mpo.2950070214.
9
External genital abnormalities associated with Wilms tumor.与肾母细胞瘤相关的外生殖器异常。
Urology. 1984 Aug;24(2):130-3. doi: 10.1016/0090-4295(84)90413-8.
10
Wilms tumor demonstrating onset and rapid growth.
J Urol. 1970 Jan;103(1):86-8. doi: 10.1016/s0022-5347(17)61898-6.
引用本文的文献
1
Genetics of Wilms' tumor.肾母细胞瘤的遗传学
Hum Genet. 1981;57(3):231-46. doi: 10.1007/BF00278936.
2
Molecular analysis of chromosome region 11p13 in patients with Drash syndrome.Drash综合征患者11p13染色体区域的分子分析。
Hum Genet. 1991 Mar;86(5):497-501. doi: 10.1007/BF00194641.
3
renal tumors and tumor-like lesions in pediatric patients.小儿患者的肾肿瘤及肿瘤样病变
Pediatr Nephrol. 1992 Jul;6(4):365-82. doi: 10.1007/BF00869741.
本文引用的文献
1
Simultaneous Wilms tumors in identical twins.同卵双胞胎同时发生肾母细胞瘤。
J Urol. 1951 Oct;66(4):547-50. doi: 10.1016/S0022-5347(17)74374-1.
2
ASSOCIATION OF WILMS'S TUMOR WITH ANIRIDIA, HEMIHYPERTROPHY AND OTHER CONGENITAL MALFORMATIONS.肾母细胞瘤与无虹膜、半侧肥大及其他先天性畸形的关联
N Engl J Med. 1964 Apr 30;270:922-7. doi: 10.1056/NEJM196404302701802.
3
Bilateral retinoblastoma: a dominantly inherited affection.双侧视网膜母细胞瘤：一种显性遗传性疾病。
Br Med J. 1972 Jun 3;2(5813):580-3. doi: 10.1136/bmj.2.5813.580.
4
Curability of cancer in children.儿童癌症的可治愈性。
Cancer. 1968 Oct;22(4):779-84. doi: 10.1002/1097-0142(196810)22:4<779::aid-cncr2820220413>3.0.co;2-y.
5
Wilms's tumor in three children of a woman with congenital hemihypertrophy.一名患有先天性半侧肥大的女性的三名子女患肾母细胞瘤。
N Engl J Med. 1974 Jul 4;291(1):23-4. doi: 10.1056/NEJM197407042910106.
6
Mutation and cancer: a model for Wilms' tumor of the kidney.突变与癌症：肾母细胞瘤模型
J Natl Cancer Inst. 1972 Feb;48(2):313-24.
7
Wilms' tumor in three successive generations.三代家族性肾母细胞瘤
Surgery. 1972 Nov;72(5):756-61.
8
Natural history and treatment of Wilms's tumour: an analysis of 335 cases occurring in England and Wales 1962-6.肾母细胞瘤的自然病史与治疗：对1962年至1966年间发生在英格兰和威尔士的335例病例的分析
Br Med J. 1970 Oct 24;4(5729):195-200. doi: 10.1136/bmj.4.5729.195.
9
Bilateral nephroblastoma in two sisters.两姐妹患双侧肾母细胞瘤。
J Urol. 1967 Feb;97(2):216-20. doi: 10.1016/S0022-5347(17)63015-5.
10
Childhood cancer in twins.双胞胎中的儿童癌症。
Cancer. 1966 Feb;19(2):157-61. doi: 10.1002/1097-0142(196602)19:2<157::aid-cncr2820190203>3.0.co;2-#.
Zotero 插件