Bond J V
Arch Dis Child. 1977 Mar;52(3):243-5. doi: 10.1136/adc.52.3.243.
Twin boys, both of whom had hypospadias and bilateral cryptorchidism, each developed a left-sided Wilms's tumour. The first twin was found to have an advanced multifocal tumour at the age of 15 months and died with local recurrence and pulmonary metastases. The diagnosis was made in the second twin one month later and at nephrectomy the tumour was found to be encapsulated without metastases; he is disease-free 12-years later. Although the histological appearances were similar in each twin, the tumours did not develop at the same rate and did not show the 'mirror-image' pattern suggested for embryonal tumours in identical twins.
一对双胞胎男孩，两人均患有尿道下裂和双侧隐睾症，各自都患上了左侧肾母细胞瘤。第一个双胞胎在15个月大时被发现患有晚期多灶性肿瘤，最终因局部复发和肺转移而死亡。一个月后在第二个双胞胎身上做出了诊断，肾切除时发现肿瘤有包膜且无转移；12年后他无病生存。尽管每个双胞胎的组织学表现相似，但肿瘤的发展速度不同，也未表现出同卵双胞胎胚胎肿瘤所提示的“镜像”模式。
