相似文献
1
Chemical validation of GPI biosynthesis as a drug target against African sleeping sickness.
EMBO J. 2004 Nov 24;23(23):4701-8. doi: 10.1038/sj.emboj.7600456. Epub 2004 Nov 4.
2
Designing sleeping sickness control.
ACS Chem Biol. 2008 Oct 17;3(10):601-3. doi: 10.1021/cb800239p.
3
Probing enzymes late in the trypanosomal glycosylphosphatidylinositol biosynthetic pathway with synthetic glycosylphosphatidylinositol analogues.
ACS Chem Biol. 2008 Oct 17;3(10):625-34. doi: 10.1021/cb800143w.
4
Identification of novel inhibitors of UDP-Glc 4'-epimerase, a validated drug target for african sleeping sickness.
Bioorg Med Chem Lett. 2006 Nov 15;16(22):5744-7. doi: 10.1016/j.bmcl.2006.08.091. Epub 2006 Sep 7.
5
Trypanosoma brucei: effects of methoprene and other isoprenoid compounds on procyclic and bloodstream forms in vitro and in mice.
Exp Parasitol. 1997 Nov;87(3):229-36. doi: 10.1006/expr.1997.4196.
6
Trypanosoma brucei CTP synthetase: a target for the treatment of African sleeping sickness.
Proc Natl Acad Sci U S A. 2001 May 22;98(11):6412-6. doi: 10.1073/pnas.111139498. Epub 2001 May 15.
7
Parasite-based screening and proteome profiling reveal orlistat, an FDA-approved drug, as a potential anti Trypanosoma brucei agent.
Chemistry. 2012 Jul 2;18(27):8403-13. doi: 10.1002/chem.201200482. Epub 2012 Jun 1.
8
Glycosyl phosphatidylinositols in Trypanosoma brucei.
Exp Parasitol. 1993 Mar;76(2):216-20. doi: 10.1006/expr.1993.1026.
9
Biosynthesis and uptake of thiamine (vitamin B1) in bloodstream form Trypanosoma brucei brucei and interference of the vitamin with melarsen oxide activity.
Int J Parasitol. 2006 Feb;36(2):229-36. doi: 10.1016/j.ijpara.2005.10.003. Epub 2005 Nov 21.
10
Discovery of halo-nitrobenzamides with potential application against human African trypanosomiasis.
Bioorg Med Chem Lett. 2010 Jan 1;20(1):149-52. doi: 10.1016/j.bmcl.2009.11.022. Epub 2009 Nov 14.
引用本文的文献
1
Structure and Function of the Glycosylphosphatidylinositol Transamidase, a Transmembrane Complex Catalyzing GPI Anchoring of Proteins.
Subcell Biochem. 2024;104:425-458. doi: 10.1007/978-3-031-58843-3_16.
2
Structures of liganded glycosylphosphatidylinositol transamidase illuminate GPI-AP biogenesis.
Nat Commun. 2023 Sep 8;14(1):5520. doi: 10.1038/s41467-023-41281-y.
3
Molecular insights into biogenesis of glycosylphosphatidylinositol anchor proteins.
Nat Commun. 2022 May 12;13(1):2617. doi: 10.1038/s41467-022-30250-6.
4
The Leishmania donovani Ortholog of the Glycosylphosphatidylinositol Anchor Biosynthesis Cofactor PBN1 Is Essential for Host Infection.
mBio. 2022 Jun 28;13(3):e0043322. doi: 10.1128/mbio.00433-22. Epub 2022 Apr 14.
5
An essential, kinetoplastid-specific GDP-Fuc: β-D-Gal α-1,2-fucosyltransferase is located in the mitochondrion of .
Elife. 2021 Aug 19;10:e70272. doi: 10.7554/eLife.70272.
6
Computational and experimental analysis of the glycophosphatidylinositol-anchored proteome of the human parasitic nematode Brugia malayi.
PLoS One. 2019 Sep 12;14(9):e0216849. doi: 10.1371/journal.pone.0216849. eCollection 2019.
7
Aspergillus fumigatus phosphoethanolamine transferase gene gpi7 is required for proper transportation of the cell wall GPI-anchored proteins and polarized growth.
Sci Rep. 2019 Apr 10;9(1):5857. doi: 10.1038/s41598-019-42344-1.
8
Interaction with Host: Mechanism of VSG Release as Target for Drug Discovery for African Trypanosomiasis.
Int J Mol Sci. 2019 Mar 25;20(6):1484. doi: 10.3390/ijms20061484.
9
Blocking variant surface glycoprotein synthesis alters endoplasmic reticulum exit sites/Golgi homeostasis in Trypanosoma brucei.
Traffic. 2018 Jun;19(6):391-405. doi: 10.1111/tra.12561. Epub 2018 Apr 6.
10
Targeting the GPI biosynthetic pathway.
Pathog Glob Health. 2018 May;112(3):115-122. doi: 10.1080/20477724.2018.1442764. Epub 2018 Feb 27.
本文引用的文献
1
Deletion of the GPIdeAc gene alters the location and fate of glycosylphosphatidylinositol precursors in Trypanosoma brucei.
Biochemistry. 2003 Dec 16;42(49):14532-40. doi: 10.1021/bi034869g.
2
Inhibitors of glycosyl-phosphatidylinositol anchor biosynthesis.
Biochimie. 2003 Mar-Apr;85(3-4):465-72. doi: 10.1016/s0300-9084(03)00065-8.
3
Essential roles for GPI-anchored proteins in African trypanosomes revealed using mutants deficient in GPI8.
Mol Biol Cell. 2003 Mar;14(3):1182-94. doi: 10.1091/mbc.e02-03-0167.
4
Prodrugs of biologically active phosphate esters.
Bioorg Med Chem. 2003 Mar 20;11(6):885-98. doi: 10.1016/s0968-0896(02)00552-7.
5
Further probing of the substrate specificities and inhibition of enzymes involved at an early stage of glycosylphosphatidylinositol (GPI) biosynthesis.
Carbohydr Res. 2002 Nov 19;337(21-23):2049-59. doi: 10.1016/s0008-6215(02)00187-8.
6
Cloning of Trypanosoma brucei and Leishmania major genes encoding the GlcNAc-phosphatidylinositol de-N-acetylase of glycosylphosphatidylinositol biosynthesis that is essential to the African sleeping sickness parasite.
J Biol Chem. 2002 Dec 20;277(51):50176-82. doi: 10.1074/jbc.M208374200. Epub 2002 Oct 2.
7
Specificities of enzymes of glycosylphosphatidylinositol biosynthesis in Trypanosoma brucei and HeLa cells.
J Biol Chem. 2002 Oct 4;277(40):37147-53. doi: 10.1074/jbc.M203371200. Epub 2002 Jul 29.
8
Purification, cloning and characterization of a GPI inositol deacylase from Trypanosoma brucei.
EMBO J. 2001 Sep 3;20(17):4923-34. doi: 10.1093/emboj/20.17.4923.
9
Specificity of GlcNAc-PI de-N-acetylase of GPI biosynthesis and synthesis of parasite-specific suicide substrate inhibitors.
EMBO J. 2001 Jul 2;20(13):3322-32. doi: 10.1093/emboj/20.13.3322.
10
Fatty acid remodeling of glycosyl phosphatidylinositol anchors in Trypanosoma brucei: incorporation of fatty acids other than myristate.
Mol Biochem Parasitol. 2001 Jul;115(2):157-64. doi: 10.1016/s0166-6851(01)00279-1.
Zotero 插件