Hodzić Mirsad, Rath Stefan, Richter Hans-Peter
Neurokirurski odjel, Univerzitetski klinicki centar Tuzla, BiH.
Med Arh. 2004;58(4):235-8.
The endovascular treatment of an intracranial aneurysm using the Guglielmi detachable coil (GDC) becomes more and more treatment of choice which is based on aneurysm configuration, aneurysm location, the patient's medical and neurological condition and age, available surgical and interventional abilities at the treatmant center, and patient preference.
Out of 73 patients with the intracranial aneurysm, 9 were treated by the endosaccular embolization using the Guglielmi detachable coil. Subarachnoid hemorrhage (SAH) occured in 8 patients and a spacio-compressive effect caused epilepsy in one patient. Three patients with multiple aneurysms were treated by the combination of microsurgical clipping and endosaccular embolization. The outcome was obtained after 6-12 months on the basis of Glasgow outcome scale.
Out of five patients treated in acute phase of severe subarachnoid hemorrhage (Hunt-Hess grade 4 and 5), one patient died for an inicial hemorrhage, one had a severe disability, and three patients had a good recovery or moderate disability. Two patients with the multiple aneurysms returned to the same quality of life as before the SAH, and one patient had moderate disability.
Microsurgical clipping of the neck of aneurysm is an optimal way of treatment for the most of ruptured intracranial aneurysms. Endosaccular embolization becomes more and more the treatment of choice in selected cases.
基于动脉瘤形态、位置、患者的医学及神经状况与年龄、治疗中心现有的手术和介入能力以及患者偏好,使用 Guglielmi 可脱卸弹簧圈(GDC)对颅内动脉瘤进行血管内治疗越来越成为治疗的首选。
在 73 例颅内动脉瘤患者中,9 例采用 Guglielmi 可脱卸弹簧圈进行瘤内栓塞治疗。8 例患者发生蛛网膜下腔出血(SAH),1 例患者因占位压迫效应引发癫痫。3 例多发性动脉瘤患者采用显微手术夹闭与瘤内栓塞联合治疗。根据格拉斯哥预后量表在 6 - 12 个月后得出结果。
在 5 例于严重蛛网膜下腔出血急性期(Hunt - Hess 分级 4 级和 5 级)接受治疗的患者中,1 例因初次出血死亡,1 例严重残疾,3 例恢复良好或中度残疾。2 例多发性动脉瘤患者恢复到与 SAH 发作前相同的生活质量,1 例中度残疾。
对大多数破裂的颅内动脉瘤而言,显微手术夹闭动脉瘤颈部是最佳治疗方式。在特定病例中,瘤内栓塞越来越成为治疗的首选。