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对替莫唑胺敏感的颅内转移性嗅神经母细胞瘤。

Intracranial metastatic esthesioneuroblastoma responsive to temozolomide.

作者信息

Wick Wolfgang, Wick Antje, Küker Wilhelm, Dichgans Johannes, Weller Michael

机构信息

Department of Neurology, University of Tübingen Medical School, Tübingen, Germany.

出版信息

J Neurooncol. 2004 Oct;70(1):73-5. doi: 10.1023/b:neon.0000040826.30636.4a.

DOI:10.1023/b:neon.0000040826.30636.4a
PMID:15527110
Abstract

Successful management of a heavily pretreated 58-year-old woman with metastatic esthesioneuoblastoma using temozolomide is reported. There is no standard treatment of this tumors with extra- and intracranial manifestations. The response, long term stability and high quality of life using temozolomide for this tumor entity should be recognized.

摘要

据报道,一名58岁接受过大量预处理的转移性嗅神经母细胞瘤女性患者使用替莫唑胺治疗成功。对于这种有颅外和颅内表现的肿瘤,尚无标准治疗方法。应认识到替莫唑胺用于该肿瘤实体时的疗效、长期稳定性和高生活质量。

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本文引用的文献

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A prospective study on glioblastoma in the elderly.一项关于老年胶质母细胞瘤的前瞻性研究。
Cancer. 2003 Feb 1;97(3):657-62. doi: 10.1002/cncr.11097.
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Treatment of intracranial metastatic esthesioneuroblastoma.颅内转移性嗅神经母细胞瘤的治疗
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Treatment of intracranial metastatic esthesioneuroblastoma.
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Genetic and molecular alterations in olfactory neuroblastoma: implications for pathogenesis, prognosis and treatment.
嗅神经母细胞瘤的遗传和分子改变:对发病机制、预后及治疗的意义
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Multimodality Treatment of Pediatric Esthesioneuroblastoma.小儿嗅神经母细胞瘤的多模态治疗
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Esthesioneuroblastoma (Olfactory Neuroblastoma) with Ectopic ACTH Syndrome: a multidisciplinary case presentation from the Joan Karnell cancer center of Pennsylvania Hospital.嗅神经母细胞瘤(嗅神经细胞瘤)伴异位 ACTH 综合征:来自宾夕法尼亚医院 Joan Karnell 癌症中心的多学科病例报告。
Oncologist. 2010;15(1):51-8. doi: 10.1634/theoncologist.2009-0016. Epub 2010 Jan 6.
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Disease stabilization of progressive olfactory neuroblastoma (esthesioneuroblastoma) under treatment with sunitinib mesylate.甲磺酸舒尼替尼治疗进展性嗅神经母细胞瘤(嗅神经上皮瘤)的疾病稳定化。
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Esthesioneuroblastoma methods of intracranial extension: CT and MR imaging findings.嗅神经母细胞瘤颅内扩展的方法:CT 和 MR 成像表现。
Neuroradiology. 2009 Dec;51(12):841-50. doi: 10.1007/s00234-009-0581-0. Epub 2009 Aug 11.
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Esthesioneuroblastoma.嗅神经母细胞瘤
Curr Treat Options Oncol. 2005 Nov;6(6):509-18. doi: 10.1007/s11864-005-0029-7.
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A phase II study of temozolomide vs. procarbazine in patients with glioblastoma multiforme at first relapse.一项针对多形性胶质母细胞瘤首次复发患者的替莫唑胺与丙卡巴肼对比的II期研究。
Br J Cancer. 2000 Sep;83(5):588-93. doi: 10.1054/bjoc.2000.1316.
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Esthesioneuroblastoma: reflections of a 21-year experience.嗅神经母细胞瘤:21年经验之反思
Laryngoscope. 1999 Oct;109(10):1539-43. doi: 10.1097/00005537-199910000-00001.
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