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验证时间与变化测试在韩国老年人中筛查痴呆症的有效性。

Validating the Time and Change test to screen for dementia in elderly Koreans.

作者信息

Rhee Jung-Ae, Chung Eun-Kyung, Shin Min-Ho

机构信息

Department of Preventive Medicine, Chonnam National University Medical School, Hak-1-dong, Dong-gu, Gwangju 501-190, South Korea.

出版信息

BMC Public Health. 2004 Nov 4;4:52. doi: 10.1186/1471-2458-4-52.

Abstract

BACKGROUND

We assessed the applicability of the T&C test as an accurate and convenient means to screen for dementia in primary care and community settings.

METHODS

The study group comprised 59 patients and 405 community participants, all of who were aged 65 years and over. The time component of the T&C test evaluated the ability of a subject to comprehend clock hands that indicated a time of 11:10, while the change component of the T&C test evaluated the ability of a subject to make 1,000 Won from a group of coins with smaller denominations (one 500, seven 100, and seven 50 Won coins).

RESULTS

The T&C test had a sensitivity and specificity of 73.0 and 90.9%, respectively, and positive and negative predictive values of 93.1, and 66.7%, respectively. The test-retest and interobserver agreement rates were both 95% (kappa = 0.91) (time interval, 24 hours). The association between the T&C test and K-MMSE test was modest, while significant (r = 0.422, p < 0.001). The T&C test scores were not influenced by educational status.

CONCLUSIONS

We conclude that the T&C test is useful as supplemental testing of important domains (e.g., calculation, conceptualization, visuospatial) to traditional measures such as the MMSE. However, because T&C test is simple, rapid, and easy to use, it can be applied conveniently to elderly subjects by non-specialist personnel who receive training.

摘要

背景

我们评估了时间与货币测试(T&C测试)作为在初级保健和社区环境中筛查痴呆症的准确且便捷方法的适用性。

方法

研究组包括59名患者和405名社区参与者,他们均为65岁及以上的老年人。T&C测试的时间部分评估受试者理解显示11:10时间的时钟指针的能力,而T&C测试的货币部分评估受试者从一组小面额硬币(一枚500韩元、七枚100韩元、七枚50韩元硬币)中凑出1000韩元的能力。

结果

T&C测试的灵敏度和特异度分别为73.0%和90.9%,阳性预测值和阴性预测值分别为93.1%和66.7%。重测信度和观察者间一致率均为95%(kappa = 0.91)(时间间隔为24小时)。T&C测试与简易精神状态检查表(K-MMSE)测试之间的关联中等,但具有显著性(r = 0.422,p < 0.001)。T&C测试分数不受教育程度影响。

结论

我们得出结论,T&C测试作为对诸如MMSE等传统测量方法中重要领域(如计算、概念化、视觉空间)的补充测试是有用的。然而,由于T&C测试简单、快速且易于使用,经过培训的非专业人员可以方便地将其应用于老年受试者。

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