Vereşiu I A
University of Medicine and Pharmacy Iuliu Hatieganu, Diabetes, Nutrition and Metabolic Diseases Department, Cluj-Napoca, Romania.
Rom J Intern Med. 2004;42(2):293-9.
Searching for more efficient treatments for diabetic neuropathy continues to be a task for researchers and for practitioners also. The reasons are: the poor quality of life and the risk for ulcerations/amputations induced by peripheral diabetic neuropathy (PDP) (the most frequent manifestation of diabetic neuropathy) and the risk for sudden death and other manifestations attributed to autonomic neuropathy. There is a paucity of evidence based interventions for PDP. In this situation, the recent evidence (randomized, placebo controlled studies) regarding the efficacy of alpha-lipoic acid, a powerful antioxidant, are bringing new hopes.
寻找更有效的糖尿病神经病变治疗方法仍然是研究人员和从业者的一项任务。原因如下：糖尿病周围神经病变（PDP，糖尿病神经病变最常见的表现形式）导致生活质量低下，存在溃疡/截肢风险，以及自主神经病变导致的猝死和其他表现的风险。针对PDP的循证干预措施匮乏。在这种情况下，最近关于强效抗氧化剂α-硫辛酸疗效的证据（随机、安慰剂对照研究）带来了新的希望。
