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DNA replication: stalling a fork for imprinting and switching.

作者信息

Egel Richard

机构信息

Department of Genetics, University of Copenhagen, Øster Farimagsgade 2A, DK-1353 Copenhagen K, Denmark.

出版信息

Curr Biol. 2004 Nov 9;14(21):R915-7. doi: 10.1016/j.cub.2004.10.012.

Abstract

Mating-type switching in fission yeast has long been known to be directed by a DNA 'imprint'. This imprint has now been firmly characterized as a protected site-specific and strand-specific nick. New work also links the widely conserved Swi1-Swi3 complex to the protection of stalled replication forks in general.

摘要

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