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[口服硫酸乙酰肝素预防术后深静脉血栓形成。与肝素钙的对照临床研究]

[The prevention of postoperative deep venous thrombosis with heparan sulfate per os. A controlled clinical study vs. heparin calcium].

作者信息

Seccia M, Bellomini M G, Goletti O, Tortora A, Buccianti P, Chiarugi M, Bertolucci A, Martino M C, Macaluso C, Cavina E

机构信息

Cattedra di Chirurgia d'Urgenza, Università degli Studi di Pisa.

出版信息

Minerva Chir. 1992 Jan;47(1-2):45-8.

PMID:1553052
Abstract

The paper reports the results of a randomised study carried out on a pool of 100 patients undergoing surgery in order to assess the efficacy and tolerability of orally administered heparan sulfate versus heparin calcium in the prevention of postoperative deep-vein thrombosis. Despite the limits of oral administration, heparan sulfate is indicated in the pharmacological prevention of postoperative deep-vein thrombosis.

摘要

该论文报告了一项针对100名接受手术患者的随机研究结果,以评估口服硫酸乙酰肝素与肝素钙在预防术后深静脉血栓形成方面的疗效和耐受性。尽管口服给药存在局限性,但硫酸乙酰肝素仍被用于术后深静脉血栓形成的药物预防。

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