Jassar P, Jose J, Homer J J
Department of Otolaryngology, York District Hospital, Wigginton Road, York, UK.
Clin Otolaryngol Allied Sci. 2004 Dec;29(6):602-5. doi: 10.1111/j.1365-2273.2004.00880.x.
Clinicians often prescribe otic drops anecdotally to try and clear grommets blocked with blood. We carried out an in vitro double-blind randomized controlled study comparing the efficacy of sodium bicarbonate, Locorten Vioform and olive oil drops in clearing Shah grommets placed in 'artificial ears' and blocked with blood in a standardized fashion. There were 33 grommets in each group, and drops were inserted three times a day for 7 days. Olive oil drops cleared 17 of 33 (51.51%), Locorten Vioform cleared one of 33 (3%) and sodium bicarbonate cleared zero of 33 (0%) blocked grommets. Statistical comparison between pairs indicates that olive oil was significantly better than both Locorten Vioform (P < 0.001) and sodium bicarbonate drops (P < 0.001) at clearing grommets blocked with blood.
临床医生常常凭经验开耳滴剂，试图清理被血液堵塞的通气管。我们进行了一项体外双盲随机对照研究，比较了碳酸氢钠、氯倍他索十一烯酸锌软膏和橄榄油滴剂在清理以标准化方式放置在“人工耳”中并被血液堵塞的沙阿通气管方面的疗效。每组有33个通气管，滴剂每天滴入3次，持续7天。橄榄油滴剂使33个堵塞通气管中的17个（51.51%）畅通，氯倍他索十一烯酸锌软膏使33个中的1个（3%）畅通，碳酸氢钠使33个堵塞通气管中的0个（0%）畅通。两两之间的统计学比较表明，在清理被血液堵塞的通气管方面，橄榄油明显优于氯倍他索十一烯酸锌软膏（P < 0.001）和碳酸氢钠滴剂（P < 0.001）。
