Heo Moonseong, Allison David B, Fontaine Kevin R
Department of Psychiatry, Weill Medical College of Cornell University, White Plains, NY, USA.
BMC Public Health. 2004 Nov 8;4:53. doi: 10.1186/1471-2458-4-53.
To estimate the association between body-mass index (BMI: kg/m2) and colorectal cancer (CRC) screening among US adults aged >or= 50 years.
Population-based data from the 2001 Behavioral Risk Factor Surveillance Survey. Adults (N = 84,284) aged >or= 50 years were classified by BMI as normal weight (18.5-<25), overweight (25-<30), obesity class I (30-<35), obesity class II (35-<40), and obesity class III (>or= 40). Interval since most recent screening fecal occult blood test (FOBT): (0 = >1 year since last screening vs. 1 = screened within the past year), and screening sigmoidoscopy (SIG): (0 = > 5 years since last screening vs. 1 = within the past 5 years) were the outcomes.
Results differed between men and women. After adjusting for age, health insurance, race, and smoking, we found that, compared to normal weight men, men in the overweight (odds ratio [OR] 1.25, 95% CI = 1.05-1.51) and obesity class I (OR = 1.21, 95% CI = 1.03-1.75) categories were more likely to have obtained a screening SIG within the previous 5 years, while women in the obesity class I (OR = 0.86, 95%CI = 0.78-0.94) and II (OR = 0.88, 95%CI = 0.79-0.99) categories were less likely to have obtained a screening SIG compared to normal weight women. BMI was not associated with FOBT.
Weight may be a correlate of CRC screening behavior but in a different way between men and women.
评估体重指数（BMI：千克/平方米）与美国50岁及以上成年人结直肠癌（CRC）筛查之间的关联。
基于2001年行为危险因素监测调查的人群数据。将年龄在50岁及以上的成年人（N = 84,284）按BMI分类为正常体重（18.5 - <25）、超重（25 - <30）、I类肥胖（30 - <35）、II类肥胖（35 - <40）和III类肥胖（≥40）。自最近一次筛查粪便潜血试验（FOBT）后的时间间隔：（0 = 自上次筛查后超过1年 vs. 1 = 在过去一年内进行过筛查），以及筛查乙状结肠镜检查（SIG）：（0 = 自上次筛查后超过5年 vs. 1 = 在过去5年内进行过筛查）为观察结果。
男性和女性的结果有所不同。在调整年龄、健康保险、种族和吸烟因素后，我们发现，与正常体重男性相比，超重（优势比[OR] 1.25，95%置信区间 = 1.05 - 1.51）和I类肥胖（OR = 1.21，95%置信区间 = 1.03 - 1.75）类别的男性在过去5年内更有可能进行过SIG筛查；而与正常体重女性相比，I类肥胖（OR = 0.86，95%置信区间 = 0.78 - 0.94）和II类肥胖（OR = 0.88，95%置信区间 = 0.79 - 0.99）类别的女性进行SIG筛查的可能性较小。BMI与FOBT无关。
体重可能是CRC筛查行为的一个相关因素，但在男性和女性中表现方式不同。
