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急性自主神经功能障碍:静脉注射免疫球蛋白两个疗程后完全康复。

Acute dysautonomia: complete recovery after two courses of IVIg.

作者信息

Ishitobi Mamiko, Haginoya Kazuhiro, Kitamura Taro, Munakata Mitsutoshi, Yokoyama Hiroyuki, Iinuma Kazuie

机构信息

Department of Pediatrics, Tohoku University School of Medicine, 1-1 Seiryo-machi, Aoba-ku, Sendai 980-8574, Japan.

出版信息

Brain Dev. 2004 Dec;26(8):542-4. doi: 10.1016/j.braindev.2004.02.012.

Abstract

An 11-year-old boy presented with acute dysautonomia manifesting as severe orthostatic hypotension following fever. Serial orthostatic tests with measurement of the coefficient of variation in the R-R intervals showed improvement after one course and complete recovery after two courses of intravenous high-dose immunoglobulin therapy (IVIg). Repeated courses of IVIg should be considered to treat this disorder if spontaneous remission does not occur.

摘要

一名11岁男孩出现急性自主神经功能障碍,表现为发热后严重的体位性低血压。连续进行体位性测试并测量R-R间期的变异系数,结果显示在接受一个疗程的大剂量静脉注射免疫球蛋白治疗(IVIg)后病情有所改善,两个疗程后完全康复。如果未出现自发缓解,应考虑重复进行IVIg疗程来治疗这种疾病。

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