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霉菌性(肺炎链球菌)主动脉瘤所致胸椎脊柱炎:一例报告

Thoracic spondylitis from a mycotic (Streptococcus pneumoniae) aortic aneurysm: a case report.

作者信息

Englert Carsten, Aebert Hermann, Lenhart Markus, Solleder Albert, Nerlich Michael, Neumann Carsten

机构信息

Department of Trauma and Reconstructive Surgery, University of Regensburg Hospital, Regensburg, Germany.

出版信息

Spine (Phila Pa 1976). 2004 Sep 1;29(17):E373-5. doi: 10.1097/01.brs.0000137061.79898.8f.

Abstract

STUDY DESIGN

We report on a 54-year-old man with chronic lower back pain after recent streptococcus pneumoniae pulmonary infection, resulting in a mycotic aortic aneurysm and spondylodiscitis of the eighth vertebrae 6 months later. Successful surgical treatment and recurrence-free survival after 4 years are described.

SUMMARY OF BACKGROUND DATA

Osteomyelitis by Streptococcus pneumoniae of the spine combined with contained rupture of a mycotic aortic aneurysm into lung and spine has not been reported to date. Mycotic aneurysms with pulmonary fistulas are reported to carry a mortality rate of up to 100%. Few cases have been reported with different operative and conservative strategies.

METHODS

The mycotic aortic aneurysm was excised using extracorporeal circulation and replaced by a Dacron graft. The spondylitic section of the eighth thoracic vertebrae was radically resected, and a tricortical bone block from the iliac crest was inserted into the defect. To keep compartments separated, collagen sponges with antibiotic supplementation were used. A triple antibiotic therapy (Metronidazol 3 x 0.5 g/day, Cefotaxim 3 x 2 g/day, and Flucloxacillin 3 x 2 g/day) was prescribed for 6 weeks and changed to Clindamycin for 1 year thereafter.

RESULTS

The patient made a good recovery and is free of recurrence 4 years after surgery.

CONCLUSIONS

Lower back pain might be a projected pain. Particularly in older patients or in the presence of comorbidities resulting in an immunocompromised status, an aggressive workup may be indicated. Radical resection of inflammatory tissues, sparse use of implant material, and prolonged administration of antibiotics proved a successful strategy in this patient.

摘要

研究设计

我们报告了一名54岁男性,近期感染肺炎链球菌后出现慢性下背痛,6个月后导致霉菌性主动脉瘤和第八节椎体的脊椎椎间盘炎。描述了成功的手术治疗及4年后无复发存活情况。

背景数据总结

肺炎链球菌引起的脊柱骨髓炎合并霉菌性主动脉瘤向肺和脊柱的局限性破裂,迄今为止尚未见报道。据报道,伴有肺瘘的霉菌性动脉瘤死亡率高达100%。采用不同手术和保守策略的病例报道较少。

方法

使用体外循环切除霉菌性主动脉瘤,并用涤纶移植物进行置换。对第八胸椎的脊椎炎节段进行根治性切除,将取自髂嵴的三层皮质骨块植入缺损处。为保持各腔隙分隔,使用补充抗生素的胶原海绵。给予三联抗生素治疗(甲硝唑3次/天,每次0.5g;头孢噻肟3次/天,每次2g;氟氯西林3次/天,每次2g),持续6周,之后改为克林霉素治疗1年。

结果

患者恢复良好,术后4年无复发。

结论

下背痛可能是牵涉痛。特别是在老年患者或存在导致免疫功能低下的合并症时,可能需要积极的检查。对炎症组织进行根治性切除、尽量少用植入材料以及延长抗生素使用时间,在该患者中证明是一种成功的策略。

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