作为小鼠I类乙醇脱氢酶（ADH1）底物的环氧化视黄醛的合成。
Synthesis of ring-oxidized retinoids as substrates of mouse class I alcohol dehydrogenase (ADH1).
作者信息
Domínguez Marta, Alvarez Rosana, Martras Sílvia, Farrés Jaume, Parés Xavier, de Lera Angel R
机构信息
Departamento de Química Orgánica, Universidade de Vigo, 36200 Vigo, Spain.
出版信息
Org Biomol Chem. 2004 Nov 21;2(22):3368-73. doi: 10.1039/B411585F. Epub 2004 Oct 11.
DOI:10.1039/B411585F
PMID:15534715
Abstract
Ring-oxidized retinoids have been synthesized stereoselectively using the Stille cross-coupling reaction. Kinetic constants of mouse class I alcohol dehydrogenase (ADH1) with these retinoids were determined.
摘要
已使用施蒂勒交叉偶联反应立体选择性地合成了环氧化视黄酸。测定了小鼠I类乙醇脱氢酶（ADH1）与这些视黄酸的动力学常数。
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