Benamar N, Laplante A F, Lahjomri F, Leblanc R M
Département de physique, Faculté des Sciences de Meknès, Université Moulay Ismaïl BP 4010 Beni M'hamed, Meknès, Morocco.
Physiol Meas. 2004 Oct;25(5):1199-210. doi: 10.1088/0967-3334/25/5/010.
A modulated photoacoustic spectroscopy study on the effect of dihydroxyacetone, commonly used for artificial tan, is presented. The study was carried out in the presence and absence of dimethylisosorbide (a solvent for dihydroxyacetone) on fresh human skin, obtained from the breast region of recent autopsy cases (two females), at a frequency of 25 Hz, which enabled us to study the effect at a depth of 30 microm in the stratum corneum and beneath. By monitoring the photoacoustic signal intensity with time in the region of 300-400 nm, which is a specific region for melanin pigment, it is demonstrated that dihydroxyacetone in combination with dimethylisosorbide enhances the process of tanning. Dihydroxyacetone also has an effect on the amino acids and nucleic acids which is bad for the skin.
本文介绍了一项关于二羟基丙酮（常用于人工晒黑）效果的调制光声光谱研究。该研究在有无二甲基异山梨醇（二羟基丙酮的一种溶剂）的情况下，对取自近期尸检病例（两名女性）乳房区域的新鲜人体皮肤进行，频率为25赫兹，这使我们能够研究角质层及其以下30微米深度处的效果。通过监测300 - 400纳米区域（黑色素的特定区域）光声信号强度随时间的变化，结果表明二羟基丙酮与二甲基异山梨醇联合使用可增强晒黑过程。二羟基丙酮对皮肤中的氨基酸和核酸也有不良影响。
