Bandelow Borwin, Charimo Torrente Aicha, Wedekind Dirk, Broocks Andreas, Hajak Göran, Rüther Eckart
Dept. of Psychiatry & Psychotherapy, The University of Göttingen, von-Siebold-Str. 5, 37075 Göttingen, Germany.
Eur Arch Psychiatry Clin Neurosci. 2004 Dec;254(6):397-405. doi: 10.1007/s00406-004-0521-2. Epub 2004 Nov 12.
Childhood traumatic experiences, rearing styles, familial mental disorders and birth risk factors have been associated with the development of social anxiety disorder.
Patients with social anxiety disorder (n=50) and healthy controls (n=120) were investigated using a retrospective interview with 203 questions.
The frequency of reports of traumatic childhood experiences was significantly higher in patients than in controls, including separation from parents, parents' marital discord, sexual abuse, familial violence, childhood illness, and other factors. On a 0-10 point 'severe trauma scale' patients had significantly higher mean scores (2.0; SD 1.28) than control subjects (0.82; SD 1.1; p<0.0001). Only 6 (12%) of the social phobic patients, but 63 (52.5%) of the controls did not report any severe traumatic events at all (chi2=24.0; p<0.0001). Compared to controls, patients described their parents' rearing styles as significantly more unfavourable. Patients reported higher rates of psychiatric disorders in their families in general, in particular anxiety disorders, depression, and suicidality. Birth risk factors did not differ between patients and controls. In a logistic regression model, the highest contribution was noted for familial anxiety disorders. Separation from parents also had a significant, but smaller influence. There was only a trend towards a significant contribution of childhood sexual abuse. Violence in the family, parental rearing styles and birth risk factors did not contribute significantly.
The present data suggest that the aetiology of social anxiety disorder is multifactorial and that familial mental disorders and separation experiences are the most important contributing factors.
童年创伤经历、养育方式、家族精神障碍和出生风险因素与社交焦虑障碍的发生有关。
采用包含203个问题的回顾性访谈对50例社交焦虑障碍患者和120名健康对照者进行调查。
患者童年创伤经历的报告频率显著高于对照者,包括与父母分离、父母婚姻不和、性虐待、家庭暴力、童年疾病及其他因素。在0至10分的“严重创伤量表”上,患者的平均得分(2.0;标准差1.28)显著高于对照者(0.82;标准差1.1;p<0.0001)。社交恐惧症患者中只有6例(12%)根本未报告任何严重创伤事件,而对照者中有63例(52.5%)未报告任何严重创伤事件(χ2=24.0;p<0.0001)。与对照者相比,患者将其父母的养育方式描述为明显更不利。患者报告其家族中精神障碍的发生率总体较高,尤其是焦虑症、抑郁症和自杀倾向。患者与对照者在出生风险因素方面无差异。在逻辑回归模型中,家族焦虑症的贡献最大。与父母分离也有显著但较小的影响。童年性虐待仅有显著贡献的趋势。家庭中的暴力、父母养育方式和出生风险因素无显著贡献。
目前的数据表明,社交焦虑障碍的病因是多因素的,家族精神障碍和分离经历是最重要