Mavroudis C, Jester J A, Jacobs S, Ebert P A
Am J Physiol. 1979 Jan;236(1):H79-83. doi: 10.1152/ajpheart.1979.236.1.H79.
Extracellular space (ECS), water, and intracellular ion concentration were determined in the normal and hypertrophied rat myocardium. Theoretical measurements of myocardial ECS based on a mathematical model (9.31%) closely approximated the observed results in the normal myocardium (12.8%) and hypertrophied myocardium (11.7%). Observed results confirmed theoretical considerations of no change in ECS with hypertrophy. ECS and water content were higher in the right ventricle than the left ventricle, but intracellular electrolytes remained unchanged. Myocardial hypertrophy did not alter these relationships.
测定了正常和肥大大鼠心肌的细胞外间隙（ECS）、水含量及细胞内离子浓度。基于数学模型对心肌ECS进行的理论测量值（9.31%）与正常心肌（12.8%）和肥大心肌（11.7%）的观测结果非常接近。观测结果证实了关于肥大时ECS无变化的理论推测。右心室的ECS和含水量高于左心室，但细胞内电解质保持不变。心肌肥大并未改变这些关系。
