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[人感染枝双腔吸虫]

[Human infection with Dicrocoelium dendriticum].

作者信息

Rack J, Adusu E, Jelinek T

机构信息

Institut für Tropenmedizin, Berlin.

出版信息

Dtsch Med Wochenschr. 2004 Nov 19;129(47):2538-40. doi: 10.1055/s-2004-835298.

Abstract

UNLABELLED

MEDICAL HISTORY AND PHYSICAL EXAMINATION: A 36-year-old German reported having had chronic-relapsing diarrhea, right upper abdominal pain and weight-loss for about two years. His last journey had taken him to Morocco three and a half years ago. The physical examination was unremarkable except for an abdominal tenderness to palpation in the right upper quadrant. LABORATORY: The serum level of bilirubin was slightly raised to 1.13 mg/dl (<1.10 mg/dl) and the level of IgE was raised to 253 U/ml (<100 U/ml). All other laboratory findings were within normal limits. Stool examinations showed eggs of Dicrocoelium dendriticum. The abdominal ultrasound was unremarkable except for mild steatosis.

TREATMENT AND COURSE

The patient denied consumption of liver or liver-products within the past weeks. Spurious infection due to eating infected liver could thus be excluded. The patient was treated for dicrocoeliasis with praziquantel (3 x 600 mg/day for three days). Further stool examinations for parasites were negative. Since the patient still had gastrointestinal discomfort, we decided to give a further therapy with triclabendazole (700 mg, single dose). Five weeks after the second treatment the patient was almost free of symptoms and stool examinations for parasites remained negative.

CONCLUSION

Dicrocoeliasis can be associated with chronic diarrhea. Stool examinations for parasites are very important in patients with gastrointestinal symptoms.

摘要

未标注

病史及体格检查:一名36岁的德国人报告称,他患有慢性复发性腹泻、右上腹疼痛并伴有体重减轻,症状持续约两年。他最后一次旅行是在三年半前前往摩洛哥。体格检查除右上腹触诊时有压痛外,无其他异常。实验室检查:血清胆红素水平略有升高至1.13mg/dl(<1.10mg/dl),IgE水平升高至253U/ml(<100U/ml)。所有其他实验室检查结果均在正常范围内。粪便检查发现有枝双腔吸虫卵。腹部超声检查除轻度脂肪变性外,无其他异常。

治疗及病程

患者否认在过去几周内食用过肝脏或肝脏制品。因此可以排除因食用受感染肝脏导致的假性感染。患者接受吡喹酮治疗双腔吸虫病(3×600mg/天,共三天)。进一步的粪便寄生虫检查结果为阴性。由于患者仍有胃肠道不适,我们决定给予三氯苯达唑进一步治疗(700mg,单次剂量)。第二次治疗五周后,患者几乎没有症状,粪便寄生虫检查仍为阴性。

结论

双腔吸虫病可能与慢性腹泻有关。对于有胃肠道症状的患者,粪便寄生虫检查非常重要。

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