Comber H, Gavin A
National Cancer Registry, Elm Court, Boreenmanna Road, Cork, Ireland.
Br J Cancer. 2004 Nov 29;91(11):1902-4. doi: 10.1038/sj.bjc.6602236.
This study used published mortality data and regression techniques to look at time trends in cervical cancer mortality between 1970 and 2000 in the UK and the Republic of Ireland. Mortality from cancer of the cervix has been declining in the UK for at least the past 30 years. The rate of decrease has been greatest in England, Wales and Scotland and has accelerated in these countries since the reorganisation of screening services in the late 1980s. Mortality in Northern Ireland is also decreasing, but at a lesser rate and without significant change over the same period. In contrast, cervical cancer mortality in the Irish Republic, which, unlike the UK, does not have comprehensive population-based screening, has been increasing by an average of 1.5% per year since 1978. The mortality rate, which was half of that in the UK in the late 1970s, now exceeds that in any of the region of the UK. The absence of population-based screening for cervical cancer in the Republic of Ireland is the most plausible explanation for these differences in trend.
本研究利用已发表的死亡率数据和回归技术,研究了1970年至2000年间英国和爱尔兰共和国宫颈癌死亡率的时间趋势。至少在过去30年里,英国宫颈癌死亡率一直在下降。英格兰、威尔士和苏格兰的下降速度最快,自20世纪80年代末筛查服务重组以来,这些国家的下降速度加快。北爱尔兰的死亡率也在下降,但速度较慢,且同期没有显著变化。相比之下,爱尔兰共和国与英国不同,没有全面的基于人群的筛查,自1978年以来,宫颈癌死亡率平均每年上升1.5%。20世纪70年代末爱尔兰共和国的死亡率是英国的一半,现在已超过英国任何一个地区。爱尔兰共和国缺乏基于人群的宫颈癌筛查,这是这些趋势差异最合理的解释。