Beral Valerie
Department of Medical Statistics and Epidemiology, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, United Kingdom.
Cancer Epidemiol. 2015 Dec;39(6):1148-51. doi: 10.1016/j.canep.2015.08.005. Epub 2015 Nov 4.
When mortality patterns for cancer of the uterine cervix were compared with trends in incidence of sexually transmitted diseases in both England and Wales and in Scotland, there were striking associations between the temporal, social class, occupational, and geographic distributions of these diseases. The data suggest that exposure to sexually transmitted infection is an important determinant of cervical cancer. Although they are still young, women born after 1940 are already experiencing increased cervical-cancer mortality. If cervical-cancer prevention and therapy remain unchanged, this generation's high risk of death from cervical cancer will probably continue to operate throughout their lives.
当将英格兰和威尔士以及苏格兰子宫颈癌的死亡率模式与性传播疾病的发病率趋势进行比较时,这些疾病在时间、社会阶层、职业和地理分布上存在显著关联。数据表明,接触性传播感染是宫颈癌的一个重要决定因素。尽管1940年以后出生的女性仍很年轻,但她们的子宫颈癌死亡率已经在上升。如果宫颈癌的预防和治疗方法保持不变,这一代人患宫颈癌的高死亡风险可能会在她们的一生中持续存在。