Shields J A, Shields C L, Rashid R C
Oncology Service, Wills Eye Hospital, Jefferson Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania 19107.
Ophthalmic Plast Reconstr Surg. 1992;8(1):62-8. doi: 10.1097/00002341-199203000-00011.
A 55-year-old woman developed marked choroidal folds in the right eye secondary to a massive tumor in the right orbit. The patient underwent a modified exenteration with debulking of the tumor, thus providing the opportunity to do a clinicopathologic correlation on the choroidal folds. Histopathologically, the orbital tumor proved to be an unusually aggressive malignant hemangiopericytoma. Microscopic examination of the globe showed that the apices of some of the folds were directed toward the retina, whereas the apices of other folds were directed toward the choroid. In contrast to popular concepts, the retinal pigment epithelium was intact at the crests of the folds toward the retinal side, while the retinal pigment epithelium was atrophic in the valleys toward the choroid.
一名55岁女性右眼因右眼眶巨大肿瘤继发明显的脉络膜皱褶。患者接受了改良眶内容剜除术并切除大部分肿瘤，从而有机会对脉络膜皱褶进行临床病理相关性研究。组织病理学检查显示，眼眶肿瘤为一种异常侵袭性的恶性血管外皮细胞瘤。对眼球的显微镜检查发现，一些皱褶的尖端指向视网膜，而其他皱褶的尖端指向脉络膜。与普遍观点不同的是，朝向视网膜一侧的皱褶嵴处视网膜色素上皮完整，而朝向脉络膜的谷底处视网膜色素上皮萎缩。
